NA Sema ye ngeri ya Sema etali ya amidated, okusinga ekola ku nkola y’obusimu obw’omu makkati. Yetaba mu makubo agakwatagana n’okulungamya obusimu obutambuza obusimu, obusimu obukola obusimu, n’okuddamu kwa situleesi. Enkola yaayo erimu obubonero obukola ku busimu (neurotrophic signaling) n’okulungamya obusimu obuyitibwa synaptic regulation, ekigifuula enkulu mu kunoonyereza ku nkola y’okutegeera n’enkola z’okukyusakyusa obusimu. Kirina obukulu bungi mu kunoonyereza ku sayansi w’obusimu n’okulungamya enneeyisa.
Peptide ejja kuweebwa nga butto ayitibwa lyophilized powder okukakasa nti enywevu nnyo.
