Cocer Peptides ye ŋlɔe 
ŋkeke 15 enye sia
NYATAKAKAWO KPLE NUSIWO WOTSƆ ƑE NYATAKAKA SIWO KAtã WOÐO LE NYATAKAKADZRAÐOƑE SIA ME LA KPLE NYATAKAKAWO kaka KPLEE NUFIAFIA ƑE TAÐOÐOWO KO.
Wotrɔ asi le atike siwo wona le nyatakakadzraɖoƒe sia ŋu na numekuku le vitro ɖeɖeko. Wowɔa numekuku le vitro (Latingbe me: *le ahuhɔ̃e me*, si gɔmee nye le ahuhɔ̃e me) le amegbetɔ ƒe ŋutilã godo. Atike siawo menye atikewo o, United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) meda asi ɖe wo dzi o, eye mele be woazã wo atsɔ axe mɔ ɖe atikewɔwɔ, dɔléle, alo dɔléle aɖeke nu, adae, alo adae o. Se de se vevie be woatsɔ atike siawo ade amegbetɔ alo lãwo ƒe ŋutilã me le mɔ ɖesiaɖe nu.
Gɔmeɖeɖe
Prostamax nye nusi do ƒome kple bioactive peptides si ɖee fia be ewɔa dɔ nyuie le prostatitis si me dɔlékui mele o si nɔa anyi didi kple nɔnɔme bubuwo dada me. Prostamax nye atike si do ƒome kple bioactive peptides. Biomodulatory peptides wɔa akpa vevi aɖe le ŋutilãa me, eye woɖɔa ŋutilã ƒe dɔwɔwɔ vovovowo abe lãmenugbagbeviwo ƒe tsitsi, vovototodedeameme, lãmenugbagbeviwo ƒe dɔwɔwɔ, kple dɔlélenutsiŋutete ƒe ŋuɖoɖowo ɖo. Abe nu mawo dometɔ ɖeka ene la, Prostamax ɖea taɖodzinu ƒe nɔnɔme tɔxɛwo fiana, vevietɔ eɖea lɔlɔ̃ si dzena le prostate lãmenugbagbeviwo ŋu fiana, eye le esia ta wodae ɖe hatsotso me be enye prostatotropic agent.
Le eƒe hatsotsowo nu la, eto vovo tso atike siwo wozãna tsã siwo wozãna tsɔ tsia ʋumenugbagbeviɣidɔ me siwo wokpɔna tso numiemiewo me tsiwo (abe saw palmetto si woɖe tso saw palmetto me ene) alo lãwo ƒe tsinyegoe me tsiwo me. Togbɔ be wozã atike siawo siwo wozãna tsã le nɔnɔmewo abe dɔlékuiwutike si me dɔlékui mele o ƒe dɔléle si nɔa anyi didi ene dada me hã la, Prostamax, kple eƒe peptide ƒe wɔwɔme tɔxɛa, na mɔnu yeye aɖe si dzi woato ada dɔléle siwo do ƒome kple ʋumenugbagbeviɣidɔ.
Mɔ̃ si wozãna
Ŋusẽ si wòkpɔna ɖe dɔdzẽ ƒe dɔwɔwɔ dzi le ʋumenugbagbeviɣidɔ si me dɔlékui mele o si nɔa anyi didi me: Le dɔléle ƒe nɔnɔme si me ʋumenugbagbeviɣidɔ si me dɔlékui mele o nɔa anyi didi me la, ʋuka me lãkusiwo toa dɔdzẽ ƒe nuwɔna vovovowo me, siwo dometɔ aɖewoe nye vuvu, ʋukawo ƒe ʋuʋu, kple ʋumenugbagbeviɣidɔ. Prostamax ɖea dɔdzẽ ƒe dzesi siawo dzi kpɔtɔna nyuie. To dɔdzẽ ƒe cytokines ƒe ɖeɖefia kple woƒe dodo dzi kpɔkpɔ me la, exea mɔ na dɔdzẽ ƒe lãmenugbagbeviwo ƒe gege ɖe lãme na wo kple woƒe dɔwɔwɔ, si wɔnɛ be dɔdzẽ ƒe ŋuɖoɖo ƒe sesẽ dzi ɖena kpɔtɔna. Ate ŋu aɖɔ chemokines ƒe wɔwɔ hã ɖo, si aɖe dɔdzẽ ƒe lãmenugbagbeviwo ƒe chemotactic ƒe ƒuƒoƒo ɖe ʋuka me lãkusiwo ŋu dzi akpɔtɔ, si ana dɔdzẽa ƒe sesẽ dzi naɖe akpɔtɔ. Le lãmenugbagbeviwo ƒe gbegblẽ si dɔdzẽ hena vɛ gome la, Prostamax ate ŋu ado lãmenugbagbeviwo ɖɔɖɔɖo kple wo gbugbɔgadzɔ ƒe mɔnuwo ɖe ŋgɔ be woalé lãkusi ƒe wɔwɔme kple dɔwɔwɔ nyuie me ɖe asi, si axe mɔ na fibrosis kple atrophy ƒe ŋgɔyiyi.
Ŋusẽkpɔɖeamedzi ɖe chromatin ƒe wɔwɔme dzi: Le lãmenugbagbeviwo ƒe molecule ƒe ɖoɖo nu la, Prostamax kpɔa ŋusẽ gã aɖe ɖe amegbetɔ ƒe lymphocyte chromatin dzi. Chromatin si le amegbetɔ ƒe ʋumenugbagbeviɣiwo me toa afɔɖeɖe eve siwo me woɖea eƒe nɔnɔme ɖa le siwo sɔ kple dzoxɔxɔ kple dzoxɔxɔ ƒe tɔtrɔ vovovowo me. Prostamax hea dzoxɔxɔ ƒe gbugbɔmam vɛ, si trɔa dzoxɔxɔ ƒe taƒoƒo eveawo yia dzoxɔxɔ si bɔbɔ wu me, eye T_d(VII) dzi ɖena kpɔtɔna 2.9°C eye T_d(VIII) dzi ɖena kpɔtɔna 1.0°C. Nudzɔdzɔ sia ɖee fia be Prostamax ate ŋu atrɔ chromatin ƒe wɔwɔme, si ate ŋu ado ƒome kple ka siwo ƒe titrime nye 30-nm ƒe ɖiɖiɖeme ɖe ka siwo ƒe titrime nye 10-nm me. Asitɔtrɔ mawo tɔgbe le chromatin ƒe wɔwɔme ŋu gakpɔa ŋusẽ ɖe domenyiŋusẽfianu ƒe ɖeɖefia kple edziwɔwɔ dzi, si wɔnɛ be wòkpɔa ŋusẽ si mele tẽ o ɖe lãmenugbagbeviwo ƒe ŋutilã ƒe dɔwɔwɔ dzi.
Ŋusẽkpɔɖeamedziwo
Dɔdzẽ dzi ɖeɖe kpɔtɔ le ʋumenugbagbeviɣidɔ si me dɔlékui mele o si nɔa anyi didi me: Aɖuɖɔtoedɔléle si me dɔlékui mele o si nɔa anyi didi nye tsinyegoe me dɔléle siwo bɔ wu dometɔ ɖeka, eye zi geɖe la, atike siwo wozãna tsã la meɖea vi o, eye zi geɖe la, egadzɔna le atikewɔwɔ vɔ megbe. Le dodokpɔ me numekukuwo me la, Prostamax ɖe dɔlékuiwutike nyui aɖe fia, eɖe dɔdzẽ si nɔa anyi didi ƒe dzesiwo dzi kpɔtɔ nyuie, eɖe ʋukawo ƒe vuvu dzi kpɔtɔ, eɖe ʋukawo ƒe ʋuʋu dzi kpɔtɔ, eye wòxe mɔ ɖe ʋumenugbagbeviɣiwo ƒe gege ɖe lãme na ame nu. Esia le vevie ŋutɔ na dɔnɔwo ƒe dzesiwo ƒe nyonyo kple woƒe agbenɔnɔ ƒe nyonyome. To dɔdzẽ dzi ɖeɖe kpɔtɔ me la, ate ŋu aɖe dɔnɔwo ƒe vevesese abe vevesese kple aɖuɖɔtoe ƒe dɔmawɔmawɔ nyuie ene dzi akpɔtɔ, si ana atikewɔwɔmɔnu yeye nyui aɖe na prostatitis si nɔa anyi didi si menye dɔlékui o.
Mɔxexe ɖe ʋuka me lãkusiwo ƒe sesẽ kple woƒe vuvu nu: Le dɔdzẽ si nɔa anyi didi ƒe dzodzo ɣeyiɣi didi te la, dɔléle ƒe tɔtrɔwo abe tsinyenye kple ʋuʋudedi ene te ŋu dzɔna bɔbɔe, si gagblẽa nu le ʋuka ƒe dɔwɔwɔ nyuie ŋu. Prostamax ate ŋu awɔ dɔ atsɔ axe mɔ ɖe dɔléle ƒe dɔwɔwɔ gbegblẽ siawo ƒe ŋgɔyiyi nu. Ewɔa esia to lãmenugbagbeviwo godo ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe dadasɔ me, xea mɔ na ka siwo me ka le ƒe dzidziɖedzi fũ akpa, eye wòtoa esia me xea mɔ na ʋuka siwo me ʋu sina tona ƒe sesẽme. To lãmenugbagbeviwo ƒe agbetsitsi kple dzidziɖedzi ƒe dzesimɔwo dodo ɖe ŋgɔ me la, eléa ʋumenugbagbevi dzĩwo ƒe xexlẽme kple dɔwɔwɔ me ɖe asi, si xea mɔ na lãmenugbagbeviwo ƒe vuvu. Esia le vevie ŋutɔ na ŋutilã ƒe wɔwɔme kple dɔwɔwɔ nyuie si le ʋuka me léle ɖe asi kple dɔlélea ƒe ŋgɔyiyi blewu.
Lãwo ƒe gbɔdɔdɔ ƒe dɔwɔwɔ dodo ɖe ŋgɔ: Le dodokpɔ siwo sɔ me la, wokpɔe be Prostamax ate ŋu ana lãwo ƒe gbɔdɔdɔ ƒe dɔwɔwɔ nanyo ɖe edzi. Ekpɔa ŋusẽ ɖe hypothalamic-pituitary-gonadal axis dzi, eye wòɖɔa gbɔdɔdɔ ƒe lãmetsiwo ƒe dodo kple woƒe dodo ɖo, si wɔnɛ be ekpɔa ŋusẽ nyui ɖe lãwo ƒe gbɔdɔdɔ ƒe dɔwɔwɔ dzi. Dɔwɔwɔ sia ɖee fia be asixɔxɔ ate ŋu anɔ Prostamax zazã ŋu le vidzidzi ƒe lãmesẽnyawo gome, menye na dɔnɔ siwo ŋu prostatitis le ɖeɖeko o ke na ameha bubu siwo ŋu gbɔdɔdɔ ƒe dɔmawɔmawɔ nyuie gblẽ nu le hã, si ate ŋu ana atikewɔwɔmɔnu yeyewo.
Ŋusẽ si wòate ŋu akpɔ ɖe chromatin ƒe dɔwɔwɔ siwo do ƒome kple domenyiŋusẽfianu ƒe wɔwɔme dzi: Esi wònye be Prostamax ate ŋu ana dzoxɔxɔ ƒe gbugbɔmamã kple wɔwɔme ƒe tɔtrɔwo nava ʋumenugbagbevi dzĩwo ƒe chromatin me ta la, togbɔ be womekpɔ ŋusẽ si wòkpɔna ɖe ŋutilã ƒe dɔwɔwɔ bliboa dzi bliboe haɖe o hã la, le nukpɔsusu nu la, tɔtrɔ mawo le chromatin ƒe wɔwɔme me ate ŋu akpɔ ŋusẽ ɖe domenyiŋusẽfianu ƒe nuŋɔŋlɔ kple eɖeɖefia dzi, si ana wòakpɔ ŋusẽ ɖe lãmenugbagbeviwo ƒe vovototodedeameme, dzidziɖedzi, kple dɔlélenutsiŋutete ƒe ɖoɖowɔwɔ ƒe dɔwɔwɔwo. Ate ŋu akpɔ ŋusẽ ɖe ŋutilãa ƒe dɔlélenutsiŋutete ƒe dɔwɔwɔ dzi le mɔ si mele tẽ o nu to domenyiŋusẽfianu vevi aɖewo ƒe ɖeɖefia dzi kpɔkpɔ me, si ana wòakpɔ ŋusẽ ɖe dɔlélenutsiŋutete ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ kple dɔwɔwɔ dzi.
Dɔbiagbalẽviwo
Atikewɔwɔ na aɖuɖɔtoedɔ si me dɔlékui mele o si nɔa anyi didi: Ne míebu Prostamax ƒe dɔwɔwɔ nyuie le dɔdzẽ dzi ɖeɖe kpɔtɔ, mɔxexe ɖe lãmenugbagbeviwo ƒe fibrosis nu, kple atrophy le prostatitis si me dɔlékui mele o si nɔa anyi didi me ta la, ŋutete nyui aɖe le esi be woate ŋu azãe le dɔléle sia dada me.
Nusiwo woate ŋu azã le vidzidzi ƒe lãmesẽ me: Esi wònye be Prostamax ate ŋu ana gbɔdɔdɔ ƒe dɔwɔwɔ nanyo ɖe edzi le lãwo me ta la, nɔnɔme sia na asixɔxɔ si woate ŋu azã le vidzidzi ƒe lãmesẽnyawo me. Le dɔnɔ siwo ŋu vidzidzi ƒe nya siwo gbɔdɔdɔ ƒe dɔmawɔmawɔ nyuie hena vɛ alo ame ɖekaɖeka siwo ƒe gbɔdɔdɔ ƒe dɔwɔwɔ dzi ɖe kpɔtɔ le ƒexɔxɔ ta gome la, Prostamax ate ŋu ado abe atikewɔmɔnu yeye ene.
Numekuku dɔwɔnu le lãmenugbagbeviwo ƒe nugbagbeŋutinunya kple molecule biology me: Ŋusẽ tɔxɛ si Prostamax kpɔna ɖe lymphocyte chromatin ƒe wɔwɔme dzi na wònye dɔwɔnu si ate ŋu anye lãmenugbagbeviwo ƒe nugbagbeŋutinunya kple molecule biology numekuku. Numekulawo ate ŋu azãe atsɔ asrɔ̃ nu tso ƒomedodo si le chromatin ƒe wɔwɔme kple domenyiŋusẽfianu ƒe ɖeɖefia ƒe ɖoɖowɔwɔ dome ŋu, eye woaku molecule ƒe mɔnu siwo le ŋutilã ƒe dɔwɔwɔ abe lãmenugbagbeviwo ƒe vovototodedeameme, dzidziɖedzi, kple dɔlélenutsiŋutete ƒe ɖoɖowɔwɔ ene te la me. Ne numekulawo tsɔ Prostamax da dɔ na lãmenugbagbeviwo la, woate ŋu akpɔ tɔtrɔ sesẽ siwo vaa chromatin ƒe wɔwɔme kple tɔtrɔ siwo do ƒome kplii le domenyiŋusẽfianu ƒe ɖeɖefia me, si ana woase lãmenugbagbeviwo me dzesiwo ƒe kadodo sesẽawo gɔme nyuie wu. Ate ŋu anye dɔwɔnu hã si woatsɔ ado domenyiŋusẽfianu yeyewo kple dzesimɔ siwo ku ɖe chromatin ƒe wɔwɔme ƒe ɖoɖowɔwɔ ŋu akpɔ ahade dzesi wo, si ana nukpɔsusu kple mɔnu yeyewo na agbeŋutinunya me numekuku.
Nyanuwuwuw
Kpuie ko la, Prostamax, abe nusi do ƒome kple bioactive peptides ene, ɖea viɖe vovovowo fiana le prostatitis si menye dɔlékui o si nɔa anyi didi dada me, siwo dometɔ aɖewoe nye dɔdzẽ dzi ɖeɖe kpɔtɔ, mɔxexe ɖe lãmenugbagbeviwo ƒe fibrosis kple atrophy nu, kple lãwo ƒe gbɔdɔdɔ ƒe dɔwɔwɔ dodo ɖe ŋgɔ. Eƒe dɔwɔwɔ ƒe mɔnuwo bia be wòaɖɔ dɔdzẽ ƒe dɔwɔwɔwo ɖo, atrɔ chromatin ƒe wɔwɔme, kple akpa bubuwo. Le eŋudɔwɔwɔ gome la, menye ɖeko ŋugbedodo le eŋu le ʋumenugbagbeviɣidɔ si menye dɔlékui o si nɔa anyi didi dada me ko o, ke asixɔxɔ le eŋu le vidzidzi ƒe lãmesẽnyawo hã me, kpakple le lãmenugbagbeviwo kple molecule ƒe nugbagbeŋutinunya me numekuku hã me.
Dzɔtsoƒewo
[1] Borovskaya T. G., Pakhomova A. V., Vychuzhanina A. V., kple ame bubuwo. Dodokpɔ me nusɔsrɔ̃ tso atike ƒe dɔwɔwɔ nyuie Prostamax le aseptic prostatitis si nɔa anyi didi kple eƒe kuxiwo dada me[J]. Egbegbe Numekuku le Dzoxɔxɔ me, 2013,Vol.02No.03:5.DOI:10.4236/mri.2013.23007.
[2] Meskhi T, Khachidze D, Barbakadze S, kple ame bubuwo. [Peptide bioregulator prostamax ƒe ŋusẽkpɔɖeamedzi ɖe amegbetɔ ƒe ʋumenugbagbevi dzĩwo ƒe heterochromatin dzi le teƒea][J]. Biofizika, 2004,49 (6): 1091-1093.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Xɔ&db=pubmed&dopt=Abstract&list_uids=15612551&biabia_hl=1
Adzɔnu si li na numekuku zazã ɖeɖeko:
