▎ TB4 ye mun ye?
TB4 (Thymosin Beta-4) ye pepitiri ye min bɛ sɔrɔ kɔnɔna na, a bɛ kɛ ni asidi aminiki 43 ye, min bɛ bɔ hadamaden timosini β4 min bɛ sɔrɔ a yɛrɛ la, o yɔrɔ koloma min bɛ baara kɛ. A bɛ ji wulicogo ɲuman ni a jɔcogo sabatili jira, a bɛ sɔrɔ a yɛrɛ la kosɛbɛ farikolo yɔrɔw la i n’a fɔ joli, farikolo ani fari, wa a bɛ se ka sɔrɔ ni fɛn dilannenw ye. Ni i ye a suma ni timosini β4 ye min ma tiɲɛ, TB4 bɛ ɲɛnamaya kɛcogo jɔnjɔn mara ka sɔrɔ a bɛ minɛ nɔgɔya la farikolo yɔrɔw fɛ pikiri fɛ. A bɛ baara kɛ k’a sɔrɔ a ma fɛn caman sɛmɛntiya, o b’a to a ye pepitiri mɔlikuluw dɔ ye minnu sɛgɛsɛgɛra kosɛbɛ farikolo yɔrɔw dilancogo la.
TB4 bɛ selilɛriw ka jiginni ni farikolo yɔrɔw labɛn kokura, a kɛtɔ ka seliluw ka jiginni seko baara minnu bɛ tali kɛ dilancogo la i n’a fɔ endoteliyali selilɛriw ani fibroblaste. A bɛ joli-sira-funu ni kolajɛ (collagène) bilali teliya, o bɛ dɛmɛ don farikolo-ɲɛnajɛ-yɔrɔw joginniw dilancogo la farikolo, senkɔniw, ligaments ani fari la. O waati kelen na, a bɛ farikolo kɔkanna matiriyali balansi labɛn walasa ka dɔ bɔ sɔgɔsɔgɔninjɛ sɔrɔli kojugu la. A bɛ funu kɛlɛli ni farikolo tangacogo jira ni a bɛ banakisɛfagalanw bɔli bali i n’a fɔ TNF-α ani IL-1β, o la, a bɛ dɔ bɔ farikolo funu ni sɔgɔsɔgɔninjɛ la. Ka fara o kan, a bɛ selilɛriw ka farikolo tangalanw degun fanga bonya, ka tiɲɛni nɔgɔya ka bɔ ischemie ni bagaw la, wa a jɔyɔrɔ ka bon farikolo joginlenw ka sigida fitinin sabatili la.
A bɛ kɛ furakɛli dɛmɛnan ye farikoloɲɛnajɛ joginw na i n’a fɔ farikolojidɛsɛ, sɔgɔsɔgɔninjɛ, ani sɔgɔsɔgɔninjɛ, o bɛ kɛnɛyali surunya ani ka dɛmɛ don farikoloɲɛnajɛ baara seginni na. Joginda kɛnɛyali la, a bɛ joginda basigilenw datuguli teliya minnu tɛ kɛnɛya (misali la, sukarodunbana senkɔniw) ani jeninida joginw ni a bɛ granulasiyɔn farikolo falenni ni epiteliyali selilɛriw ka jiginni sabati. Farikolo tiɲɛni fɛɛrɛw la, a bɛ nafa jira fana farikolojidɛsɛ la (misali la, farikolo yɔrɔw sɔgɔsɔgɔli) ani dusukun tantanni kɔfɛ dilancogo kalanw na.
Kuncɛli
BPC-157/TB4 Blend ye sigida ye min bɛ kɛ ni pepitiri kɔnɔna fila ye minnu bɛ farikolo dilan baara kɛ. BPC-157, min bɛ bɔ hadamaden kɔnɔbara basigilen na, asidi aminiki 15 bɛ a la, ka sɔrɔ TB4 ye timosini β4 yɔrɔ baarakɛta ye, asidi aminiki 43 bɛ min na. Ni u farala ɲɔgɔn kan, u bɛ ɲɔgɔndɛmɛ nɔ bila. BPC-157 bɛ fibroblaste caya sabati, ka mucosal barrier integrity sabati, ani ka pro-inflammatory factor bɔli bali, ka sɔrɔ TB4 bɛ actin polimerizasiyɔn ɲɛnabɔ, ka selilɛriw ka jiginni teliya, ani ka joli-sira-funu lawuli. U faralen ɲɔgɔn kan, u bɛ farikolo yɔrɔw labɛncogo kura ni u dilancogo ɲuman sabati, ni banakisɛfagalan wɛrɛw ye, ka kɔnɔnatumuw lakana, ani ka selilɛriw ka sigida fitininw ɲɛ. Sisan baarakɛcogo ɲininiw sinsinnen bɛ farikoloɲɛnajɛ joginw kɛnɛyali kan (misali la, sɔgɔsɔgɔninjɛ, farikolojidɛsɛ, ligament joginw); kɔnɔbara basigilen lakanani (misali la, kɔnɔbara basigilen, banakɔtaa funubana faralen ɲɔgɔn kan); ani farikolo yɔrɔ caman tiɲɛni jɛɲɔgɔnya seginni (misali la, fari joginda, kɔnɔbara jogin misɛnninw). Nin fɛɛrɛ dafalen in bɛ dilancogo surunya, ka funu jaabiw dɔgɔya, ani ka dɛmɛ nɔgɔya farikolo yɔrɔw tiɲɛni koɲɛw la.
A sɛbɛnbaga ko la
Fɛn minnu kofɔlen dòn san fɛ, olu bɛɛ ɲinini Kɛra, k’u Labɛn ani k’u Lajɛ Cocer Peptides fɛ.
BƐƐRƐ KUNNAFONIW NI FƐRƐW KUNNAFONIW BƐƐ MIN BƐ NI WEBSITE KAN NA, olu BƐ KUNNAFONIW FƆLƆ DƆRƆN NI KALANSENW YE.
Fɛn minnu bɛ di nin siti in kan, olu dabɔra ɲininiw dɔrɔn kama in vitro. Sɛgɛsɛgɛli in vitro (latinkan na: *in glass*, o kɔrɔ ye gilasi minɛnw na) bɛ kɛ hadamaden farikolo kɔkan. Nin fura ninnu tɛ furaw ye, Ameriki dumuniko ni furako ɲɛmɔgɔso (FDA) ma sɔn u ma, wa u man kan ka kɛ ka furakɛli bana, bana walima bana si bali, k’a furakɛ, walima k’a furakɛ. A dagalen don kosɛbɛ sariya fɛ ka nin fɛn ninnu don hadamaden walima bagan farikolo la cogo o cogo.
