▎ Nukae nye TB4?
TB4 (Thymosin Beta-4) nye peptide si le lãmenugbagbeviwo me si me amino acid 43 le, si wokpɔ tso amegbetɔ ƒe thymosin β4 si le dzɔdzɔme nu ƒe nuto vevitɔ si wɔa dɔ me. Eɖea tsi ƒe ʋeʋẽ nyuie kple eƒe wɔwɔme ƒe liƒo nyuie fiana, le dzɔdzɔme nu la, edzena le lãmekawo abe ʋu, lãmeka, kple ŋutigbalẽ ene me ŋutɔ, eye woate ŋu akpɔe to mɔnu siwo wotsɔ lãnuwo wɔe dzi. Ne wotsɔe sɔ kple thymosin β4 si me gblẽ o la, TB4 léa nugbagbewo ƒe dɔwɔwɔ veviwo me ɖe asi esime lãkusiwo xɔae bɔbɔe to atike dodo me. Ewɔa dɔ evɔ mehiã be woawɔ tɔtrɔ sesẽwo o, si wɔe be wònye peptide molecule siwo ŋu wosrɔ̃ nu tsoe wu le lãmenugbagbeviwo ɖɔɖɔɖo me la dometɔ ɖeka.
TB4 doa lãmenugbagbeviwo ƒe ʋuʋu kple lãmenugbagbeviwo ƒe gbugbɔgadzɔ ɖe ŋgɔ to lãmenugbagbevi siwo do ƒome kple ɖɔɖɔɖo abe lãmenugbagbevi siwo le lãkusi me kple fibroblasts ene ƒe ʋuʋu ƒe ŋutete wɔwɔ me. Enaa ʋukawo ƒe dzɔdzɔ kple collagen ƒe sisi kabakaba, si kpena ɖe ame ŋu le lãmekawo, lãkusiwo, lãkusiwo, kple ŋutigbalẽ ƒe abi siwo le lãmekawo, lãkusiwo, kple ŋutigbalẽ me la ɖɔɖɔɖo me. Le ɣeyiɣi ma ke me la, eɖɔa lãmenugbagbeviwo godo ƒe matriki ƒe dadasɔ ɖo be wòaɖe abi ƒe dzɔdzɔ fũ dzi akpɔtɔ. Eɖea dɔlékuiwutike kple lãmenugbagbeviwo takpɔkpɔ ƒe ŋusẽkpɔɖeamedzi fiana to mɔxexe ɖe dɔlékuiwutikewo abe TNF-α kple IL-1β ene ƒe dodo nu, si wɔnɛ be lãmenugbagbeviwo ƒe dɔdzẽ kple ʋuʋu dzi ɖena kpɔtɔna. Gakpe ɖe eŋu la, enaa lãmenugbagbeviwo ƒe nuteɖeamedzi ƒe tsitretsitsi ɖe antioxidant ŋu dzina ɖe edzi, eɖea nusiwo ischemia kple aɖi gblẽna le ame ŋu dzi kpɔtɔna, eye wòwɔa akpa vevi aɖe le lãmenugbagbevi siwo xɔ abi ƒe nuto suewo ƒe liƒolili me.
Wozãnɛ abe atike kpeɖeŋutɔ na abi siwo dona tso kamedefefewo me abe lãmekawo ƒe tete, lãkusi ƒe ʋuʋu, kple lãkusiwo ƒe vuvu ene, si wɔnɛ be dɔyɔyɔ ƒe ɣeyiɣia nɔa kpuie eye wòkpena ɖe kamedefefewo ƒe dɔwɔwɔ gbugbɔgaɖoanyi ŋu. Le abi ƒe dɔyɔyɔ me la, enaa abi siwo mewɔa dɔ o siwo nɔa anyi didi (le kpɔɖeŋu me, suklidɔ ƒe afɔ ƒe abi) ƒe nutsotso kabakaba kple abi siwo woxɔna le dzobibi me to granulation tissue ƒe tsitsi kple epithelial cell migration dodo ɖe ŋgɔ me. Le lãmenugbagbeviwo ƒe gbegblẽ ƒe nudede eme me la, eɖea dɔwɔwɔ nyuie hã fiana le lãmekawo ƒe abixɔxɔ (le kpɔɖeŋu me, lãmeka siwo le gota ƒe ʋuʋu) kple dzitodzito me ʋu ƒe sisi megbe numekukuwo me.
Nyanuwuwuw
BPC-157/TB4 Blend nye ɖoɖo si wowɔ ɖekae si me peptide eve siwo le lãmenugbagbeviwo me siwo si lãmenugbagbeviwo ɖɔɖɔɖo ƒe dɔwɔwɔ le. Amino acid 15 le BPC-157, si woɖe tso amegbetɔ ƒe dɔgbo ƒe lãkusi me protein me, gake TB4 nye thymosin β4 ƒe kakɛ si le dɔ wɔm, si me amino acid 43 le. Ne wotsɔ wo ƒo ƒui la, wowɔa dɔ aduadu. BPC-157 doa fibroblast ƒe dzidziɖedzi ɖe ŋgɔ, enaa mucosal barrier ƒe blibonyenye nyona ɖe edzi, eye wòtsia pro-inflammatory factor ƒe dodo nu, gake TB4 ya ɖɔa actin polymerization ɖo, enaa lãmenugbagbeviwo ƒe ʋuʋu kabakaba, eye wòʋãa ʋukawo ƒe dzɔdzɔ. Ne wotsɔ wo katã ƒo ƒui la, wodoa lãmenugbagbeviwo ƒe gbugbɔgadzɔ kple wo dzadzraɖo nyuie ɖe ŋgɔ, eye wowɔa dɔ bubu siwo tsia dɔdzẽ nu, wokpɔa ŋutinuwo ta, eye wònaa lãmenugbagbeviwo ƒe nuto suewo nyona ɖe edzi. Fifia ƒe dɔwɔwɔ ŋuti numekukuwo ku ɖe kamedefefewo ƒe abixɔxɔ ƒe hayahaya ŋu (le kpɔɖeŋu me, lãkusidɔ, lãmekawo ƒe tete, lãkusi ƒe abixɔxɔ); dɔgbo ƒe ʋukawo takpɔkpɔ (le kpɔɖeŋu me, dɔgbo ƒe abi, dɔgbo ƒe dɔléle si naa dɔdzẽ kpena ɖe ame ŋu); kple lãmeka geɖe ƒe nugbegblẽ ƒe nuwɔwɔ aduadu ƒe gbugbɔgaɖoanyi (le kpɔɖeŋu me, ŋutigbalẽ ƒe abi, ŋutigbalẽ ƒe abi suewo). Mɔnu sia si kpena ɖe wo nɔewo ŋu la naa nuwo ɖɔɖɔɖo ƒe ɣeyiɣiwo nɔa kpuie, eɖea dɔdzẽ ƒe ŋuɖoɖowo dzi kpɔtɔna, eye wònaa nudede nya siwo ku ɖe lãmenugbagbeviwo ƒe gbegblẽ ŋu me nɔa bɔbɔe.
Le Agbalẽŋlɔla La Ŋu
Nusiwo míeyɔ ɖe etame la katã nye esiwo ŋu Cocer Peptides wɔ numekuku le, trɔ asi le wo ŋu eye woƒo wo nu ƒu.
NYATAKAKAWO KPLE NUSIWO WOTSƆ ƑE NYATAKAKA SIWO KAtã WOÐO LE NYATAKAKADZRAÐOƑE SIA ME LA KPLE NYATAKAKAWO kaka KPLEE NUFIAFIA ƑE TAÐOÐOWO KO.
Wotrɔ asi le atike siwo wona le nyatakakadzraɖoƒe sia ŋu na numekuku le vitro ɖeɖeko. Wowɔa numekuku le vitro (Latingbe me: *le ahuhɔ̃e me*, si gɔmee nye le ahuhɔ̃e me) le amegbetɔ ƒe ŋutilã godo. Atike siawo menye atikewo o, United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) meda asi ɖe wo dzi o, eye mele be woazã wo atsɔ axe mɔ ɖe atikewɔwɔ, dɔléle, alo dɔléle aɖeke nu, adae, alo adae o. Se de se vevie be woatsɔ atike siawo ade amegbetɔ alo lãwo ƒe ŋutilã me le mɔ ɖesiaɖe nu.
