Garagaza 70mg lend Kuvanga）

▎ Bpc157

BPC 157 ni peptide yubukorikori igizwe na acide amine cumi nagatanu, kandi izina ryayo ryuzuye ni umubiri urinda umubiri 157. Iyi molekile yabanje kuboneka mugutandukanya poroteyine mumitobe yigifu hanyuma ikayihindura muburyo bwa artile. Ubushakashatsi bwerekana ko BPC 157 ifite ibikorwa byinshi byibinyabuzima, harimo guteza imbere gusana ingirabuzimafatizo, neuroprotection, anti-ibisebe, anti-inflammatory, na antioxydeant. Mu rwego rwo gusana ingirangingo, BPC 157 irashobora kwihutisha cyane uburyo bwo gukiza ingirangingo zihuza nkuruhu, imitsi, na ligaments, cyane cyane bikerekana imbaraga nziza mugusana ibikomere byahiye. Uburyo bwibikorwa bukubiyemo kongera imbaraga zo gukwirakwiza, kwimuka, hamwe nubushobozi bwo gukora ingirabuzimafatizo ya endoteliyale, bityo bigatera angiogenezi no kuvugurura ingirangingo. Ku bijyanye na neuroprotection, BPC 157 igira uruhare runini muri sisitemu yo hagati yo hagati igenga urwego rwa neurotransmitter nka serotonine na dopamine, kandi irashobora kunoza ibibazo nka indigestion, malabsorption, na immunodeficiency.

Byongeye kandi, BPC 157 yerekana ibintu byingenzi birwanya ibisebe ndetse no kurwanya inflammatory, bishobora kugumana ubusugire bwa mucosa gastrointestinal kandi bikarinda kwanduza indwara n’uburozi mu mara. Mu rwego rwo kurinda umwijima, iyi molekile igira ingaruka zikomeye zo kurinda imikorere y’umwijima mu gukumira ikwirakwizwa ry’uturemangingo rudasanzwe, kugumana ubusugire bw’imiterere ya hepatocytes, guhagarika ibimenyetso byerekana imisemburo, kugabanya urwego rw’ibibyimba, no guhagarika inzira ya fiboside y’umwijima. Ugereranije n’ibindi biyobyabwenge, ibyiza bya BPC 157 biri muburozi bwayo buke no kutagira ingaruka zikomeye, byerekana umutekano mwiza no kwihanganira muburyo butandukanye bwinyamaswa. Kugeza ubu, BPC 157 ntabwo ifite ingaruka zidasanzwe zo kuvura mu kuvura indwara zo mu gifu ahubwo inerekana indangagaciro zishobora gukoreshwa mu guteza imbere ingirabuzimafatizo, kunoza imikorere ya sisitemu yo hagati y’imitsi, ndetse no mu rwego rwo kurwanya gusaza.

 ▎ Bpc157

Nka tripeptide yumuringa isanzwe, GHK-Cu ni molekile ikora cyane. Imiterere yibanze ni urwego ruhamye rwakozwe na tripeptide ya glycine-histidine-lysine na ion z'umuringa. Muguhindura imikorere ya metabolike yingirakamaro ya ion z'umuringa, iyi molekile yerekana ibikorwa byinshi byibinyabuzima, harimo antioxydeant, anti-inflammatory, no guteza imbere synthesis ya kolagen. Mu rwego rwubwiza no kwita ku ruhu, GHK-Cu irashobora kugabanya neza gusaza kwuruhu, kwihutisha uburyo bwo gukira ibikomere, kongera ubworoherane bwuruhu, kandi icyarimwe bigira ingaruka zikomeye zo kurwanya inflammatory na antioxydeant. Byongeye kandi, ibikorwa by’ibinyabuzima bigaragarira no mu guteza imbere ubuzima bw’imisatsi, kugenzura imiterere ya gene, no gufasha mu kuvura indwara zihariye. Nka molekile igaragara, GHK-Cu yerekana imbaraga zikomeye zo gutinda gusaza, kuzamura ibidukikije byuruhu, no kongera ubushobozi bwo gusana ingirangingo. Uburyo bwibikorwa byinshi byibikorwa biha amahirwe menshi yo gukoreshwa mubijyanye n'ubwiza, kurwanya gusaza, no kuvura. Ubushakashatsi bugezweho burerekana kandi ko GHK-Cu ishobora kumenya agaciro kayo ikoreshwa muri siyanse ya biomedicine na cosmetique ikoresheje uburyo bwinshi nko kugenzura inzira zerekana ibimenyetso, kongera ibikorwa byimikorere ya selile, no guhuza ibidukikije byangiza ibidukikije.

Incamake​

Gukoresha hamwe TB4, BPC157, na GHK-Cu bifite ingaruka nyinshi ninyungu mugukiza ibikomere, gusana ingirangingo, kurwanya inflammatory, neuroprotection, hamwe nubuzima bwuruhu nubwiza.

1.Ubuzima bwuruhu nubwiza

Kunoza uruhu rworoshye: 

GHK-Cu irashobora guteza imbere umusaruro wa kolagen na elastine, bigatuma uruhu rukomera kandi rukaba rworoshye. Kolagen na elastine nibintu byingenzi bigumana uruhu rworoshye. Ingaruka ya GHK-Cu irashobora kongera ubworoherane bwuruhu no kugabanya isura yiminkanyari n'imirongo myiza. TB4 na BPC157 birashobora guteza imbere gusana no kuvugurura ingirangingo zuruhu. Birashobora kwihutisha gukira ibikomere byuruhu, kugabanya inkovu, kandi icyarimwe bigatera metabolisme yingirangingo zuruhu, bigatuma uruhu rugira ubuzima bwiza.

Gukoresha hamwe ibi bintu bitatu birashobora kugira ingaruka zikomeye mukurwanya gusaza no kwita kuburuhu. Bikora ku ruhu hamwe, bitezimbere ubuzima nigaragara ryuruhu muburyo butandukanye, bigatuma uruhu ruba ruto kandi rukagira imbaraga.

Guteza imbere gusana uruhu: 

Kubikomere byuruhu nko gutwika, gutwika, no gukata, ibi bintu bitatu birashobora kwihutisha uburyo bwo gukiza uruhu no kugabanya inkovu. BPC157 yerekanye ingaruka zikomeye mugutezimbere gukira ibikomere byuruhu muburyo bwimbeba ya alkali yaka. Irashobora kwihutisha gufunga ibikomere no guteza imbere imitsi ya granulation, kongera epithelialisation, kuvugurura dermal, hamwe no kubika kolagen ^[1] . TB4 na GHK-Cu birashobora kandi kwihutisha uburyo bwo gukiza uruhu biteza imbere ingirabuzimafatizo no gusana, ndetse no gukora kolagen.

2. Gukiza ibikomere no gusana imyenda

Kwihutisha gukira ibikomere: 

TB4 na BPC157 zombi zifite ingaruka zo guteza imbere gukira ibikomere. TB4 irashobora kwihutisha kwimuka kwakagari no gukwirakwira, guteza imbere angiogenez, no kwihutisha synthesis ya kolagen no gusana ingirangingo. BPC157 nayo ikora neza muriki kibazo. Irashobora gutuma habaho umusaruro wa nitide ya okiside kandi igatera kwimuka kwimitsi ya endoteliyale yimitsi, bityo kwihuta gukira.

GHK-Cu ifasha uruhu kugarura ubushobozi bwo kwikosora mugutezimbere umusaruro wa kolagen na elastine. Kolagen na elastine nibintu byingenzi bigize urugingo rwuruhu, kandi umusaruro wabyo urafasha gukira ibikomere no gusana ingirangingo.

Iyo ibi bintu bitatu bikoreshejwe hamwe, ingaruka zabyo zishobora kurushaho kwihuta gukira ibikomere no kugabanya igihe cyo gukira. Ibintu bitatu biteza imbere gukira ibikomere muburyo butandukanye. TB4 na BPC157 biteza imbere cyane kwimuka kwakagari, gukwirakwizwa, na angiogenez, mugihe GHK-Cu iteza imbere umusaruro wa kolagen na elastine. Munsi yibikorwa, igikomere gishobora gukira vuba.

Kunoza ubwiza bwo gusana imyenda: 

TB4 igira uruhare mu gusana gahunda neza. Irashobora kugenga imikurire no gutandukanya no guteza imbere uburyo busanzwe bwo gusana ingirangingo, bigatuma imyenda yasanwe neza. BPC157 irashobora kuzamura ubunyangamugayo no gutuza kwinyama. Kurugero, mubushakashatsi bwokuvura imitsi, BPC157 yazamuye imikurire ya fibroblast ya tendon ivuye mubushakashatsi bwa tendon, kongera ubuzima bwimikorere ya selile mubihe bitesha umutwe, kandi biteza imbere kwimuka kwakagari, bishobora gufasha kuzamura ubusugire nuburinganire bwimitsi ^[2] . GHK-Cu irashobora guteza imbere kuvugurura ingirabuzimafatizo zuruhu. Ingirangingo zuruhu zigira uruhare runini mugusana ingirangingo. Barashobora gutandukanya ingirabuzimafatizo zitandukanye zuruhu, bigatuma ingirangingo zasanwe zifite ubuzima bwiza kandi bworoshye.

3. Ingaruka zo kurwanya inflammatory

Kugabanya igisubizo kibabaza: 

BPC157 na TB4 byombi bifite imiti igabanya ubukana. Nka antioxydeant, GHK-Cu irashobora kandi gutesha agaciro radicals yubusa itangwa mugihe cyo gutwika, bikagabanya no gutwika. Radikal yubusa irashobora kwangiza ingirangingo mugihe cyo gutwika, kandi ingaruka za antioxydeant ya GHK-Cu zirashobora kugabanya ibisekuruza byubusa, bityo bikagabanya igisubizo cyakongejwe.

Gukoresha hamwe ibi bintu bitatu birashobora kugira ingaruka nziza zo kuvura mugukiza indwara zanduza nka arthritis hamwe no gutwika imitsi. Bagira ingaruka zo kurwanya inflammatory ziva muburyo butandukanye, kandi iyo zikoreshejwe hamwe, zishobora kubyara imbaraga kandi bikagabanya neza igisubizo cyo gutwika.

4. Neuroprotection hamwe no gusana imitsi

Guteza imbere gusana imitsi: 

BPC157 igira ingaruka zo kurinda sisitemu y'imitsi, ishobora guteza imbere gukura no gusana ingirabuzimafatizo no kunoza imikorere y'imitsi. Kurugero, ubushakashatsi bumwe bwerekanye ko ingaruka zo kurinda BPC157 kuri sisitemu yimitsi ishobora kuba ifitanye isano nogukora inzira ya Src-Cav-1-eNOS ^[3] . GHK-Cu itanga ibidukikije byiza byo gukura kwingirabuzimafatizo mu guteza imbere umusaruro wa kolagen. Collagen nayo igira uruhare runini mumyanya myakura. Irashobora gutanga infashanyo nintungamubiri zingirabuzimafatizo kandi igatera imbere gukura no gusana ingirabuzimafatizo.

Ingaruka ziterwa niyi ngingo uko ari eshatu zirashobora gufasha kuvura ibikomere byimitsi nindwara zifata ubwonko nkindwara ya Parkinson nindwara ya Alzheimer. Ibintu bitatu biteza imbere gusana imitsi kuva muburyo butandukanye. BPC157 na TB4 bikora ku buryo butaziguye ingirabuzimafatizo kugira ngo biteze imbere no gusana, mu gihe GHK-Cu igira uruhare rutaziguye mu kuzamura imikurire y'utugingo ngengabuzima.

Ibyerekeye Umwanditsi

Ibikoresho byavuzwe haruguru byose byakorewe ubushakashatsi, byahinduwe kandi byakozwe na Cocer Peptides.

Imirongo ijyanye

[1] Huang T, Zhang K, Sun L, n'abandi. Umubiri urinda umubiri-157 wongera ibikomere bya alkali-gutwika gukira muri vivo kandi bigatera ikwirakwizwa, kwimuka, na angiogenezi muri vitro. Ibiyobyabwenge Byabigenewe 2015; 9: 2485-99.DOI: 10.2147 / DDDT.S82030.

[2] Impinduka C, Tsai W, Lin M, Hsu Y, Pang JS. Ingaruka zo guteza imbere pentadecapeptide BPC 157 mugukiza imitsi zirimo gukura kw'imitsi, kubaho kwakagari, no kwimuka kwakagari. J APPL PHYSIOL 2011; 110 (3): 774-80.DOI: 10.1152 / japplphysiol.00945.2010.

[3] Hsieh M, Lee C, Chueh H, n'abandi. Ingaruka zo guhindura BPC 157 kuri tone ya vasomotor no gukora kwa Src-Caveolin-1-endoteliyale nitric oxyde synthase inzira. SCI REP-UK 2020; 10(1): 17078.DOI: 10.1038 / s41598-020-74022-y.

INGINGO ZOSE N'AMAKURU Y’IBICURUZWA BITANZWE KURI URU RUBUGA BISANZWE KUBONA AMAKURU N'INTEGO Z'UBUREZI.  

Ibicuruzwa byatanzwe kururu rubuga bigenewe gusa mubushakashatsi bwa vitro. Mu bushakashatsi bwa vitro (Ikilatini: * mu kirahure *, bisobanura mu bikoresho by'ibirahure) bikorwa hanze y'umubiri w'umuntu. Ibicuruzwa ntabwo ari imiti, ntabwo byemejwe n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA), kandi ntigomba gukoreshwa mu gukumira, kuvura, cyangwa gukiza indwara iyo ari yo yose y’ubuvuzi, indwara, cyangwa indwara. Birabujijwe rwose n'amategeko kwinjiza ibyo bicuruzwa mumubiri wabantu cyangwa inyamaswa muburyo ubwo aribwo bwose.