▎ Nukae nye BPC-157?
BPC-157 wɔa nugbagbewo ƒe dɔwɔna siwo le go geɖe me to molecule veviwo abe ʋukawo ƒe lãmenugbagbeviwo ƒe tsitsi ƒe nuwɔna, lãmenugbagbeviwo ƒe nitric oxide synthase, kple tsitsi ƒe lãmetsiŋusẽ xɔlawo ƒe ɖeɖefia dzi kpɔkpɔ me, si ɖea dɔwɔwɔ nyuie etɔxɛe fiana le lãmenugbagbeviwo ɖɔɖɔɖo kple wo takpɔkpɔ me. Edoa fibroblast ƒe ʋuʋu kple collagen ƒe wɔwɔ ɖe ŋgɔ, enaa ʋukawo ƒe wɔwɔ kabakaba, eye wònaa nunyiame ƒe kpekpeɖeŋu kple ɖɔɖɔɖo ƒe ŋusẽ geɖe lãmenugbagbevi siwo gblẽ, si wɔnɛ be wokpɔa lãmenugbagbeviwo takpɔkpɔ le ɖoɖo nu.
Le dɔgbo ƒe dɔwɔwɔ me la, asixɔxɔ si le eŋu la ɖe dzesi ŋutɔ: edzraa dɔgbo ƒe ʋuka siwo gblẽ ɖo nyuie, etsia abi siwo aha alo NSAID hena vɛ nu, eɖea abi ƒe teƒe dzi kpɔtɔna, eye wòdoa dɔyɔyɔ ɖe ŋgɔ. Le dɔgbo ƒe dɔléle siwo naa dɔdzẽ abe ulcerative colitis kple Crohn ƒe dɔléle ene gome la, eɖea pro-inflammatory factor ƒe dodo dzi kpɔtɔna, eɖea dɔgbo ƒe dɔdzẽ dzi kpɔtɔna, enaa nuwo ɖɔɖɔɖo kabakaba le anastomotic teƒewo, eye wònaa dɔgboa ƒe dɔwɔwɔ nyona ɖe edzi.
Le lãmekawo kple ƒunukpeƒewo me la, BPC-157 naa mɔ siwo do ƒome kple lãkusi ƒe lãmenugbagbeviwo ƒe dzidziɖedzi kple ʋuʋu, doa ŋusẽ gbugbɔgaɖɔɖo le lãkusi kple lãkusi ƒe abixɔxɔ megbe eye wònaa hayahaya ƒe ɣeyiɣiwo nɔa kpuie le kamedefefe ƒe abi alo amekoko megbe. Enaa ƒu ƒe gbagbãƒewo ƒe dɔyɔyɔ kple ƒunukpeƒewo ƒe gbugbɔgadzɔ hã kabakaba, eɖea ƒunukpeƒewo ƒe dɔdzẽ dzi kpɔtɔna, eye wòkpɔa ŋusẽ nyui ɖe nɔnɔmewo abe ƒunukpeƒetetedɔ ene dzi.
Le ahɔhɔ̃mekawo takpɔkpɔ gome la, etrɔa asi le hippocampal domenyiŋusẽfianu ƒe ɖeɖefia ŋu le aklã ƒe abixɔxɔ ƒe kpɔɖeŋuwo me be wòakpe ɖe lãmekawo ƒe dɔwɔwɔ ŋu wòahaya. Eɖea ahɔhɔ̃mekawo ƒe gbegblẽ si ahɔhɔ̃mekawo ƒe ʋu ƒe sisi hena vɛ dzi kpɔtɔna, eɖea ahɔhɔ̃mekawo ƒe dɔmawɔmawɔ nyuie le ʋusɔgbɔdɔ megbe dzi kpɔtɔna, eye wòɖea dzesiwo dzi kpɔtɔna le Parkinson ƒe dɔléle kple tagbɔdɔléle ƒe kpɔɖeŋuwo me, si ɖea ahɔhɔ̃mekawo takpɔkpɔ ƒe ŋutete fiana. BPC-157 doa dɔyɔyɔ ɖe ŋgɔ le abi siwo woxɔ le dzobibi, esiwo me nuveviwɔame le, kple esiwo woxɔ le dɔwɔwɔ vɔ megbe me. To ʋu ƒe sisi yi ʋuka siwo me ʋu sina tona me nyuie wu me la, enaa atikewɔwɔ me viɖewo nɔa ʋu ƒe sisi ƒe dɔlélewo ŋu.
Nyanuwuwuw
TB500, KPV, kple BPC-157 ƒe kadodo ɖekae le Coremend tsakatsaka me ɖoa cascade regulatory network si nye 'anti-inflammatory - repair - regeneration' cascade regulatory network, si ɖoa nugbagbeŋusẽ ƒe ŋusẽkpɔɖeamedzi siwo katã gbɔ akpa ɖekaɖekawo mate ŋu akpɔ o gbɔ. KPV tsɔa nutoa me lãmenugbagbeviwo ƒe dɔdzẽ dzi ɖeɖe kpɔtɔ ɖoa nɔƒe gbãtɔ to mɔxexe ɖe dɔlékui si doa ŋgɔ na dɔlékuiwo ƒe dodo nu, si wɔnɛ be nuto sue si me dɔdzẽ mele fũ o si anyo na wo dzadzraɖo emegbe. Eƒe ʋumenugbagbeviɣidɔ ƒe dzidziɖedzi kple ʋuʋu dodo ɖe ŋgɔe dzea nuwo ɖɔɖɔɖodɔa gɔme le teƒe siwo gblẽ. Le gɔmeɖoanyi sia tutuɖo me la, TB500 naa lãmenugbagbeviwo ƒe ʋuʋu kabakaba to actin ƒe dɔwɔwɔ dzi kpɔkpɔ me esime wòle ʋukawo ƒe wɔwɔme kple collagen ƒe wɔwɔme ʋãm le ɣeyiɣi ɖeka me, si naa nusi dzi woanɔ te ɖo adzra lãmenugbagbeviwo ƒe wɔwɔme ɖo. Eƒe kadodoŋusẽ ƒe gbugbɔgadzɔ ƒe gɔmedzedze wɔa ɖekawɔwɔ ɖe wo nɔewo yome kple KPV ƒe dɔdzẽ dzi ɖuɖu le gɔmedzedzea me. BPC-157 doa ʋukawo ƒe wɔwɔme ƒe dɔwɔwɔ ɖe ŋgɔ to ʋukawo ƒe lãmenugbagbeviwo ƒe tsitsi ƒe akpa kple lãmenugbagbeviwo ƒe nitric oxide synthase ƒe molecule ƒe ɖeɖefia dzi ɖeɖe kpɔtɔ me, esime wòdoa fibroblast ƒe dɔwɔwɔ ɖe ŋgɔ. Esia doa ŋusẽ TB500 ƒe ʋukawo ƒe dɔwɔwɔ be wòakpɔ egbɔ be nunyiamewo nasu ame si eye wòɖea nusiwo gblẽ le evelia ŋu le edzadzraɖo me dzi kpɔtɔna to eƒe lãmenugbagbeviwo takpɔkpɔ ƒe dɔwɔwɔ me. Eƒe lãmeka geɖe ɖɔɖɔɖo ŋutetewo (dɔgbo ƒe dɔwɔwɔ, lãmekawo ƒe dɔwɔwɔ, lãmekawo ƒe dɔwɔwɔ) kpena ɖe TB500 ƒe kadodoŋusẽ ƒe gbugbɔgadzɔ kple KPV ƒe lãkusi ɖɔɖɔɖo ŋu to lãmenugbagbeviwo ƒe dɔwɔwɔ aduadu si woɖo taɖodzinu na me. Ne wowɔ ɖeka la, KPV ƒe dɔwɔwɔ si tsia dzodzodzoetsitsi nu ɖea mɔxenuwo ɖa le nuwo ɖɔɖɔɖo ŋu, TB500 ƒe gbugbɔgawɔ gɔmedzedze ɖoa xɔtuɖoɖo ƒe gɔmeɖoanyiwo anyi, eye BPC-157 ƒe dɔwɔwɔ ƒe nyonyome kple lãmenugbagbeviwo takpɔkpɔ doa nuwo ɖɔɖɔɖo ƒe nyonyome kple dɔwɔwɔ nyuie ɖe dzi. Ne wotsɔ wo katã ƒo ƒui la, wowɔa dɔ bliboa kabakaba tso dɔdzẽ ƒe ɖeɖeɖa dzi va ɖo xɔtuɖoɖowo gbugbɔgatu kple dɔwɔwɔ ƒe hayahaya le lãkusi siwo gblẽ me, si naa nudede dɔa me ƒe kpɔɖeŋu si wɔa dɔ aduadu ŋutɔ na lãmenugbagbeviwo ƒe abi sesẽwo kple dɔléle siwo do ƒome kple dɔdzẽ.
Le Agbalẽŋlɔla La Ŋu
Nusiwo míeyɔ ɖe etame la katã nye esiwo ŋu Cocer Peptides wɔ numekuku le, trɔ asi le wo ŋu eye woƒo wo nu ƒu.
NYATAKAKAWO KPLE NUSIWO WOTSƆ ƑE NYATAKAKA SIWO KAtã WOÐO LE NYATAKAKADZRAÐOƑE SIA ME LA KPLE NYATAKAKAWO kaka KPLEE NUFIAFIA ƑE TAÐOÐOWO KO.
Wotrɔ asi le atike siwo wona le nyatakakadzraɖoƒe sia ŋu na numekuku le vitro ɖeɖeko. Wowɔa numekuku le vitro (Latingbe me: *le ahuhɔ̃e me*, si gɔmee nye le ahuhɔ̃e me) le amegbetɔ ƒe ŋutilã godo. Atike siawo menye atikewo o, United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) meda asi ɖe wo dzi o, eye mele be woazã wo atsɔ axe mɔ ɖe atikewɔwɔ, dɔléle, alo dɔléle aɖeke nu, adae, alo adae o. Se de se vevie be woatsɔ atike siawo ade amegbetɔ alo lãwo ƒe ŋutilã me le mɔ ɖesiaɖe nu.
