Coremend (TB4, KPV, BPC157) 25mg + 10mg + 10mg (Blend)

▎ KPV yog dab tsi?

KPV yog ib qho tripeptide compound uas muaj lysine (Lys), proline (Pro), thiab valine (Val). Nws yog ib qho active fragment ntawm α-melanocyte-stimulating hormone (α-MSH) nrog rau cov kev ua lom lom. KPV exerts nws cov teebmeem los ntawm kev tiv thaiv kab mob thiab kho cov ntaub so ntswg txhawb nqa. Nws modulates inflammatory cytokine theem, inhibits pro-inflammatory mediator tso tawm, thiab alleviates zos inflammatory teb. Nyob rau tib lub sijhawm, nws txhawb nqa kev tsiv teb tsaws ntawm tes thiab kev loj hlob, ua kom nrawm kho thiab rov tsim dua ntawm cov mucosa puas lossis cov ntaub so ntswg los tsim kom muaj qhov chaw zoo rau kev kho mob. Nws tus nqi kho mob tseem ceeb nyob hauv kev kho cov kab mob inflammatory. Rau cov kab mob ulcerative colitis, KPV tau muab tshuaj rau hauv lub qhov quav lossis qhov ncauj (feem ntau txhim kho nrog nanocarriers lossis hydrogels rau kev txhim kho lub hom phiaj) txo qis cov kab mob colonic, kho cov mucosal puas, txo cov kab mob kev ua ub no, thiab txhawb kev kho mob colonic morphology. Hauv dermatology, KPV's anti-inflammatory zog thiab melanocyte-txhim kho cov teebmeem raug tshawb nrhiav rau kev kho mob vitiligo. Cov txheej txheem kev xa khoom boost melanin synthesis thiab cell proliferation, pab repigmentation ntawm cov tawv nqaij cuam tshuam. Tsis tas li ntawd, nws cov khoom kho cov ntaub so ntswg muaj peev xwm kho tau rau lwm yam kev raug mob mucosal lossis mob ntsig txog mob.

▎ BPC-157 yog dab tsi?

BPC-157 exerts multifaceted biological kev ua ub no los ntawm kev tswj cov kev qhia ntawm cov molecules tseem ceeb xws li vascular endothelial kev loj hlob yam, endothelial nitric oxide synthase, thiab loj hlob hormone receptors, qhia tshwj xeeb kev ua tau zoo ntawm cov ntaub so ntswg kho thiab tiv thaiv. Nws txhawb nqa fibroblast migration thiab collagen synthesis, accelerates angiogenesis, thiab muab cov ntaub so ntswg puas nrog cov khoom noj khoom haus txaus txhawb nqa thiab kho lub zog, ua tiav cov txheej txheem ntawm kev tiv thaiv cellular.

Hauv kev siv plab hnyuv, nws tus nqi yog qhov tseem ceeb: nws zoo kho plab hnyuv puas tsuaj, tiv thaiv kab mob los ntawm cawv los yog NSAIDs, txo qhov mob hauv cheeb tsam, thiab txhawb kev kho mob. Rau cov kab mob inflammatory plob tsis so tswj xws li ulcerative colitis thiab Crohn tus kab mob, nws txo cov pro-inflammatory factor tso tawm, alleviates plab hnyuv o, accelerates kho ntawm anastomotic qhov chaw, thiab txhim kho plab hnyuv.

Nyob rau hauv lub cev musculoskeletal, BPC-157 activates txoj kev muaj feem xyuam rau tendon cell proliferation thiab migration, txhawb regenerative kho tom qab tendon thiab ligament raug mob thiab shortening lub sij hawm rov qab los tom qab kis las raug mob los yog phais. Nws kuj tseem ua kom cov pob txha tsis zoo thiab kho pob txha mos, txo cov pob qij txha, thiab ua rau muaj kev cuam tshuam zoo xws li osteoarthritis.

Hais txog neuroprotection, nws modulates hippocampal gene qhia nyob rau hauv tus txha caj qaum raug mob qauv los pab lub cev muaj zog muaj nuj nqi rov qab. Nws alleviates neuronal puas tsuaj los ntawm cerebral ischemia, txo neurological deficits tom qab mob stroke, thiab txo cov tsos mob nyob rau hauv cov qauv ntawm Parkinson tus kab mob thiab schizophrenia, qhia tau hais tias muaj peev xwm neuroprotective. BPC-157 txhawb kev kho mob hauv qhov kub hnyiab, raug mob, thiab mob tom qab phais. Los ntawm kev txhim kho cov ntshav khiav mus rau cov ntaub so ntswg ischemic, nws muab cov txiaj ntsig kho mob rau cov kab mob ischemic.

Xaus

Kev sib koom ua ke ntawm TB500, KPV, thiab BPC-157 hauv Coremend sib xyaw tsim kom muaj kev tswj hwm kev sib koom tes ntawm 'anti-inflammatory - kho - rov tsim dua tshiab' cascade kev tswj hwm network, ua tiav cov txiaj ntsig lom neeg tsis tuaj yeem ua tiav los ntawm tus kheej cov khoom. KPV tseem ceeb txo qis cov ntaub so ntswg hauv zos los ntawm inhibiting pro-inflammatory factor tso tawm, tsim kom muaj cov kab mob me me uas tsim nyog rau kev kho tom ntej. Nws kev txhawb nqa ntawm mucosal cell proliferation thiab tsiv teb tsaws pib kho cov txheej txheem hauv cov chaw puas. Ua raws li lub hauv paus no, TB500 ua kom cov cell tsiv teb tsaws los ntawm kev tswj cov actin dynamics thaum ib txhij stimulating angiogenesis thiab collagen synthesis, muab cov khoom hauv paus rau kev kho cov ntaub so ntswg. Nws pib ntawm kev sib txuas ntawm cov ntaub so ntswg rov tsim ua ib qho kev sib koom ua ke nrog KPV qhov kev tiv thaiv kab mob thaum ntxov. BPC-157 txhim kho angiogenesis efficiency los ntawm upregulating molecular qhia ntawm vascular endothelial kev loj hlob yam tseem ceeb thiab endothelial nitric oxide synthase, thaum boosting fibroblast kev ua. Qhov no ua kom muaj zog TB500's angiogenic cuam tshuam los xyuas kom meej cov khoom noj khoom haus thiab txo qis kev puas tsuaj thaum lub sij hawm kho los ntawm nws txoj haujlwm cytoprotective. Nws muaj peev xwm kho cov ntaub so ntswg ntau (kab mob plab, kab mob musculoskeletal, lub paj hlwb) ntxiv rau TB500's connective cov ntaub so ntswg thiab KPV's mucosal kho los ntawm cov ntaub so ntswg-targeted synergy. Thaum muaj kev sib koom ua ke, KPV qhov kev tiv thaiv kab mob tshem tawm kev kho cov teeb meem, TB500 qhov kev pib tsim kho tshiab tsim cov qauv tsim, thiab BPC-157 qhov kev ua haujlwm zoo thiab kev tiv thaiv ntawm tes txhawb kev kho kom zoo thiab ua haujlwm zoo. Ua ke, lawv ua kom tag nrho cov txheej txheem los ntawm kev daws teeb meem mob mus rau cov qauv kev tsim kho thiab kev ua haujlwm zoo hauv cov ntaub so ntswg puas, muab cov qauv kev sib koom ua ke zoo heev rau cov ntaub so ntswg raug mob thiab cov kab mob o.

Hais Txog Tus Sau

Cov ntaub ntawv hais saum toj no yog txhua yam tshawb fawb, kho thiab sau los ntawm Cocer Peptides.

Tag nrho cov kab lus thiab cov ntaub ntawv ntawm cov khoom lag luam muab rau ntawm lub vev xaib no tsuas yog rau cov ntaub ntawv tshaj tawm kev tshaj tawm thiab cov hom phiaj kev kawm.  

Cov khoom muab rau hauv lub vev xaib no yog npaj tshwj xeeb rau kev tshawb fawb hauv vitro. Kev tshawb fawb hauv vitro (Latin: * hauv iav *, lub ntsiab lus hauv iav) yog ua los ntawm tib neeg lub cev. Cov khoom no tsis yog tshuaj, tsis tau txais kev pom zoo los ntawm US Food and Drug Administration (FDA), thiab yuav tsum tsis txhob siv los tiv thaiv, kho, lossis kho txhua yam mob, kab mob, lossis mob. Nws raug txwv nruj raws li txoj cai los qhia cov khoom no rau hauv tib neeg lossis tsiaj lub cev hauv txhua daim ntawv.