Klow 80mg (Blend)

Menene BPC-157?

BPC-157 shine peptide na roba wanda ya ƙunshi amino acid 15. Jerin sa ya samo asali ne daga guntun Kariyar Jiki (BPC) a cikin sunadaran ƙwayoyin mucosal na ɗan adam, wanda ke aiki azaman analog na wucin gadi na peptides masu kariya na gastrointestinal endogenous. Babban sifar nazarin halittu na wannan peptide ya ta'allaka ne a cikin ƙarfin ikon gyara nama. Yana haɓaka haɓakawa da ƙaura na ƙwayoyin da ke da alaƙa da gyare-gyare kamar fibroblasts da ƙwayoyin endothelial ta hanyar kunna masu karɓar tyrosine kinase (misali, c-Met), yayin haɓaka haɓakawa da sake fasalin abubuwan matrix na waje (misali, collagen, fibronectin). An tabbatar da wannan tasirin a cikin nau'ikan cututtukan ciki na ciki, raunin jijiya, da lahani na kashi. A cikin nau'ikan rauni na mucosal na ciki, BPC 157 yana rage maƙarƙashiya lokacin warkarwa kuma yana haɓaka ingancin farfadowa na mucosal.

BPC 157 yana aiki mai mahimmanci ta hanyar daidaita ƙananan ƙananan ƙwayoyin cuta. Yana hana infiltration na neutrophil da kuma wuce gona da iri na abubuwan da ke haifar da kumburi (irin su IL-1β da NF-κB), yayin da lokaci guda ke haɓaka ɓoyewar abubuwan da ke haifar da kumburi (irin su IL-10). Wannan yana rage mummunan martanin kumburi bayan rauni kuma yana hana lalacewar nama na biyu wanda kumburin mara ƙarfi ya haifar. Ana bayyana tasirin sa na vasoprotective musamman. Ta hanyar ƙaddamar da ƙaddamar da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (VEGF) da angiopoietin, yana inganta samar da sabon hanyar sadarwa na jijiyoyin jini a cikin yankunan da aka lalace, yana inganta zubar da jini na gida, kuma yana samar da isasshen abinci mai gina jiki da iskar oxygen don gyaran nama.

▎ Menene KPV?

KPV, wani tripeptide wanda ya ƙunshi lysine-proline-valine, ya samo asali ne daga yankin C-terminal na α-melanocyte-stimulating hormone (α-MSH) kuma wani yanki ne na halitta wanda ke faruwa tare da ayyukan ilimin halitta.

A cikin ƙa'idodin kumburi, KPV yana nuna aikin anti-mai kumburi mai ƙarfi. Yana da kyau yana dakatar da hanyar siginar nukiliya-κB (NF-κB), yana rage rubutun da kuma sakin cytokines na pro-inflammatory (irin su IL-1β, TNF-α, da dai sauransu), ta haka yana hana ƙumburi mai kumburi a tushen su. A cikin nau'ikan dabbobi na colitis, gudanar da baka na KPV yana rage matakan kumburi na hanji da rage lalacewar mucosal. Wannan tasirin ya samo asali ne daga ƙayyadaddun tsarin sa na siginar kumburi a cikin ƙwayoyin rigakafi na hanji da ƙwayoyin epithelial. KPV yana ƙara rage martanin kumburi na gida ta hanyar daidaita ƙwayoyin mast da rage sakin masu shiga tsakani kamar histamine, don haka kiyaye homeostasis nama.

A matakin immunoregulatory, KPV yana nuna ikon daidaitawa na bidirectional. Yana haɓaka bambance-bambancen T-cell da aiki, yana haɓaka ɓoyewar abubuwan rigakafi kamar IL-2 da IFN-γ, kuma yana haɓaka martanin rigakafi na salula. A cikin nau'ikan cututtukan cututtuka na autoimmune, KPV yana daidaita ma'aunin tantanin halitta Th1/Th2, yana rage yawan halayen autoimmune, kuma yana hana lalacewar rigakafi.

KPV kuma yana riƙe da yuwuwar ƙima a haɓakar salon salula da gyaran nama. Ta hanyar kunna hanyoyin siginar intracellular masu dacewa, yana haɓaka haɓakar fibroblast da ƙaura, yana haɓaka haɓakar abubuwan matrix na waje kamar collagen, kuma yana sauƙaƙe warkar da rauni a cikin kyallen takarda kamar fata da tsoka. A cikin gwaje-gwajen gyare-gyaren fata, raunin da aka yi wa KPV ya nuna saurin saurin waraka da rage samuwar tabo, yana nuna ingantaccen tasirinsa akan ingancin gyaran nama. KPV kuma na iya tayar da maganganun abubuwan da ke da alaƙa da angiogenesis kamar haɓakar haɓakar haɓakar ƙwayoyin cuta (VEGF), haɓaka haɓakar haɓakar jijiyoyin jini da haɓaka samar da jini zuwa wuraren da suka ji rauni, ta haka ne ke samar da mahimman yanayi don farfadowa na nama.

▎ Menene GHK-Cu?

GHK-Cu wani hadadden tsari ne da glycyl-L-histidyl-L-lysine tripeptide da jan karfe ions suka yi. Yin amfani da aikin haɗin gwiwa na ions jan karfe da tripeptide, yana yin ayyuka masu mahimmanci masu yawa a cikin ayyukan ilimin lissafi. A cikin gyaran fata da sake farfadowa, yana aiki azaman peptide mai siginar don haifar da fibroblasts don haɗakar da collagen, elastin, da glycosaminoglycans, haɓaka ƙarfin fata da elasticity yayin inganta al'amuran fata ta hanyar tsufa ko hoto. A lokacin warkar da rauni, yana ƙarfafa haɓakar ƙwayar ƙwayar ƙwayar ƙwayar cuta don haɓaka ƙulli yayin da yake daidaita kumburi ta hanyar hana IL-6 wuce kima da magana TNF-α. Hakanan yana haɓaka haɓakar macrophage don sakin abubuwan haɓakawa, taimakawa gyaran nama da gyare-gyare. Abubuwan da ke da ƙarfi na antioxidant da anti-inflammatory suna daidaita matakan jan ƙarfe na cikin salula, haɓaka ƙarfin antioxidant, da jinkirta tsufa na salula. A cikin nau'ikan kumburin huhu, yana rage lipopolysaccharide mai saurin kamuwa da cutar huhu kuma yana inganta jihohin kumburin nama. GHK-Cu yana da amfani ga lafiyar gashi ta hanyar haɓaka aikin ƙwayar gashi, haɓaka samar da melanin, daidaita ƙarfin kuzari, da kuma taimakawa ga haɓaka asarar gashi.

Kammalawa

A matsayin haɗuwa da tarin tarin fuka 500, BPC-157, KPV, da GHK-Cu, tasirin haɗin gwiwar Klow yana bayyana ta hanyar daidaitawa da ƙarin ƙa'idodi na ayyuka na ilimin lissafin jiki da yawa. TB 500 yana inganta ƙaurawar kwayar halitta da angiogenesis, BPC-157 yana haɓaka gyaran nama da ƙa'idodin kumburi, KPV yana mai da hankali kan ma'auni na rigakafi da ƙwayar cuta ta gida, yayin da GHK-Cu ke aiki a cikin tsaro na antioxidant, farfadowa na fata, da ingantawa na microenvironment. Tare, sun samar da tsarin rufaffiyar madauki na 'gyara-anti-ƙumburi-nau'i-nau'i-nau'i-nau'in haɓakawa.'

A ƙarƙashin wannan haɗin gwiwa, TB 500 da BPC-157 suna haɓaka haɓakar ƙwayoyin cuta da haɓakar matrix, yayin da KPV ke rage ƙumburi mai yawa ta hanyar hana hanyar NF-κB, samar da ingantaccen yanayi don gyarawa. Abubuwan antioxidant na GHK-Cu suna rage lalacewar radical kyauta ga sabbin kyallen takarda, kuma tasirin sa na vasoprotective yana aiki tare da aikin angiogenesis na TB 500 don haɓaka wadatar jini na gida. KPV's bidirectional immunization modulation yana daidaita aikin rigakafi wanda BPC-157 da GHK-Cu suka haifar, yana hana dysregulation na rigakafi. Wannan haɗin gwiwa ba wai yana rage hawan hawan nama ba kawai amma yana inganta ingancin gyarawa kuma yana rage haɗarin samuwar tabo, yana ba da fa'idodi masu fa'ida a cikin al'amuran kamar warkar da rauni, kumburi na yau da kullun, da tsufa na fata.

Game da Marubuci

Abubuwan da aka ambata a sama duk bincike ne, gyara su kuma Cocer Peptides ne suka haɗa su.

DUK LABARI DA BAYANIN KAYAYYA DA AKE BAYAR A WANNAN SHAFIN KAWAI DOMIN WATSA BAYANI NE DA MANUFOFIN ILIMI.  

Kayayyakin da aka bayar akan wannan gidan yanar gizon an yi niyya ne kawai don binciken in vitro. Binciken in vitro (Latin: *a cikin gilashi*, ma'ana a cikin gilashin gilashi) ana gudanar da shi a wajen jikin mutum. Waɗannan samfuran ba magunguna ba ne, Hukumar Abinci da Magunguna ta Amurka (FDA) ba ta amince da su ba, kuma dole ne a yi amfani da su don hanawa, magani, ko warkar da duk wani yanayi na likita, cuta, ko cuta. Doka ta haramta shigar da waɗannan samfuran cikin jikin mutum ko dabba ta kowace hanya.