Esi lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe dɔlélewo abe lolo akpa, lolo akpa, kple suklidɔ ene ƒe dzɔdzɔ yi edzi le dzidzim ɖe edzi le xexeame katã la, atike siwo wɔa dɔ nyuie wu didi va zu nyati vevi aɖe le atikewɔwɔ me. Xlẽ Nu Geɖe

Lãmetsiŋusẽ ƒe dɔwɔwɔ kple lãmenugbagbeviwo ƒe dɔwɔwɔ ɖɔa amegbetɔ ƒe ŋutilã ƒe asitɔtrɔ, ŋusẽ ƒe dadasɔ, kple tsitsi kple tsitsi to lãmetsiŋusẽ ƒe kadodo deŋgɔ aɖe dzi. Xlẽ Nu Geɖe

Numekuku peptidewo nye molecule siwo wowɔ le dɔwɔwɔ nyuie siwo wowɔ le nudokpɔƒewo, siwo ƒe asixɔxɔ vevitɔe nye be woana dɔwɔnu siwo woatsɔ ado alɔ agbeŋutinunya ŋuti numekuku eye woazã wo le numekuku siwo wowɔna le vitro ɖeɖeko me. 'In vitro numekuku,' si woɖe tso Latingbe me nya 'in vitro' (si gɔmee nye 'le glass me'), fia koŋ numekuku siwo wowɔ le dodokpɔ ƒe nɔnɔme siwo dzi wokpɔna kple asi, abe lãmenugbagbeviwo ƒe dekɔnu, molecule ƒe kadodo me dzodzro, alo biochemical reaction assays ene. Xlẽ Nu Geɖe

Peptide kadodo nye covalent kadodo si ɖe dzesi le protein moleculewo me, si wowɔ to tsikuɖiɖi ƒe tsinyenye ƒe dɔwɔwɔ me le amino acid ɖeka ƒe α-carboxyl ƒuƒoƒo (α-COOH) kple amino acid si te ɖe eŋu ƒe α-amino ƒuƒoƒo (-NH2) dome. Eƒe atike ƒe nɔnɔme nye amide ƒe kadodo. Xlẽ Nu Geɖe

Amino acid nye lãmenugbagbeviwo ƒe ƒuƒoƒo si me α-amino ƒuƒoƒo (α-NH2) kple α-carboxyl ƒuƒoƒo (α-COOH) le, eye woƒe nɔnɔme bliboa nye RCH(NH2)COOH. Wotsɔ α-carbon atɔm la do ƒome kple axadzikɔsɔkɔsɔ ƒe ƒuƒoƒo aɖe koŋ (R ƒuƒoƒo), si nye nugbagbewo ƒe molecule gãwo ƒe wɔwɔme ƒe akpa veviwo. Xlẽ Nu Geɖe

Peptide ŋuti kɔklɔ nye peptide tsakatsaka ƒuƒu siwo wokpɔ to wo wɔwɔ alo wo ɖeɖefia me la mama kple wo dodo ɖe ŋgɔ to dzɔdzɔmeŋusẽ, atikewo, alo nugbagbeŋutinunya ƒe mɔnuwo zazã me be woakpɔ peptide siwo woɖo taɖodzinu na siwo le dzadzɛ ŋutɔ. Xlẽ Nu Geɖe

Peptide ƒe ʋeʋẽ fia peptide ƒe agbɔsɔsɔ si sɔ gbɔ wu si ateŋu alɔ ɖe ʋeʋẽ ƒe lolome ɖeka me le dzoxɔxɔ kple pH ƒe nɔnɔme tɔxɛwo me, si ƒe dzesi zi geɖe enye agbɔsɔsɔme ƒe agbɔsɔsɔ (g/L) alo molar ƒe agbɔsɔsɔme (mol/L). Abe dzɔdzɔmeŋusẽŋununya ƒe nɔnɔme vevi aɖe ene la, ekpɔa ŋusẽ ɖe peptidewo ƒe xɔxlɔ̃, wo mama, woƒe lãmenugbagbeviwo ƒe dɔwɔwɔ, kple wo ɖeɖe ɖa (ADME) ƒe dɔwɔwɔwo dzi tẽ le agbe me, eye wòfiaa atike siwo wotu ɖe peptide dzi ƒe dzadzraɖo mɔ̃ɖaŋununya, wo dzadzraɖo ƒe liƒo, kple wo zazã nyuie le dɔdaƒe hã. Xlẽ Nu Geɖe

Peptide ƒe ƒuƒoƒo, le woƒe amino acid ƒe ɖoɖo tɔxɛwo kple teƒe ƒe wɔwɔme ta, ƒe nɔnɔme nye be woƒe nugbagbewo ƒe dɔwɔnawo te ŋu gblẽa nu le gotagome nutome ƒe ŋusẽkpɔɖeamedziwo ŋu bɔbɔe ŋutɔ. Susu vevitɔ si ta woadzra peptide ɖoe nye be woaxe mɔ ɖe atikewo ƒe dɔwɔwɔ abe woƒe gbegblẽ, oxidation, kple ƒoƒo ƒu nu, si ana woƒe wɔwɔme ƒe blibonyenye kple nugbagbewo ƒe dɔwɔwɔ nanɔ anyi. Xlẽ Nu Geɖe

Dermorphin wɔa eƒe vevesesenutsitikewo koŋ to nuwɔwɔ kple μ-opioid receptor (MOP) me. μ-opioid xɔla nye opioid xɔla ƒe ƒomea me tɔ vevi aɖe eye wòwɔa akpa vevi aɖe le vevesese ƒe tɔtrɔ me. Xlẽ Nu Geɖe