TB 500 (Thymosin Beta-4 Fragment 17-23) bụ iberibe bioactive jikọtara ya na ọtụtụ isi usoro na physiology mmadụ, karịsịa na nrụzi anụ ahụ na mbugharị cell. GỤKWUO

Usoro ahụ ji alụso ọrịa ọgụ na-ejigide homeostasis nke anụ ahụ site na netwọk dị mgbagwoju anya nke mkpụrụ ndụ na ụmụ irighiri ihe, ebe mmeghachi omume mgbochi dysregulated nwere ike ibute ọrịa, mbufụt na-adịghị ala ala, ma ọ bụ ọrịa autoimmune. Isi ihe na-achịkwa usoro ahụ ji alụso ọrịa ọgụ, mbelata mbufụt, na ọgwụgwọ adjuvant maka ọrịa autoimmune dabere na ntinye aka nke ọma na ịgbalite cell mgbochi ọrịa, ụzọ mgbama ọkụ, yana usoro nnabata nke mgbochi. Dị ka mkpụrụ ndụ ihe nketa bioactive, peptide bekee, na ebumnuche ha dị elu na nkọwapụta biocompatibility, nwere ike gbanwee ọrụ cell na-egbochi ọrịa, gbochie ntụgharị mgbaàmà pro-inflammatory, ma gbanwee microenvironment nke na-alụso ọrịa ọgụ, na-enye ihe ngwọta ọhụrụ maka ọgwụgwọ ọrịa na-efe efe, ọrịa autoimmune, na ọnọdụ metụtara mbufụt. GỤKWUO

Okwu ịka nká na akpụkpọ ahụ na-ebilite site na ngwakọta nke ọtụtụ ihe, gụnyere usoro isi dị ka mfu collagen, mmebi nrụgide oxidative, ntinye nke melanin, mkpirisi telomere, na mbelata na metabolism ike cellular. Ihe peptide, dị ka mkpụrụ ndụ bioactive, na-egosipụta uru pụrụ iche na mbelata wrinkle, ụkpụrụ melanin, nchebe telomere, antioxidation, na ịcha akpụkpọ ahụ n'ihi oke ebumnuche ha dị iche iche na biocompatibility. Site n'iṅomi peptides sitere n'okike ma ọ bụ na-ebuli ihe owuwu molekụla, ihe ndị a na-etinye aka kpọmkwem na ụzọ ịka nká akpụkpọ ahụ, na-edozi mmebi na ọkwa cellular ma na-emegharị udidi akpụkpọ ntorobịa, si otú a na-enye ihe ngwọta ọhụrụ maka mgbochi ịka nká na cosmetology ahụike. GỤKWUO

Na mgbakwunye na ngalaba isi dị ka usoro metabolic na mgbochi mgbochi mkpali, ihe ndị peptide na-egosipụta uru pụrụ iche na ọnọdụ pụrụ iche gụnyere itinye aka na ọrịa iku ume, nchebe ọrụ obi, na mmepe ngwa nyocha nnwale, n'ihi oke nhazi ha dị iche iche na ọrụ ndu. Ngwa ndị a na-agbaji na njedebe nke ọgwụ ọdịnala, na-enye ihe ngwọta ọhụrụ maka ọgwụgwọ ọrịa mgbagwoju anya na nchọpụta sayensị bụ isi site na nrụzi mucosal ezubere iche na usoro iku ume, nhazi nke ụzọ mgbaàmà cell cardiovascular, na njikwa ziri ezi nke ụdị nnwale. Uru ha bụ isi - nkọwapụta ebumnuche dị elu, obere immunogenicity, na nhazi nhazi - na-eme ka mgbasawanye nke peptides sitere na ọgwụgwọ ụlọ ọgwụ gaa na ngwa multidisciplinary. GỤKWUO

Imeju, dị ka akụkụ dị n'etiti maka metabolism na detoxification na ahụ mmadụ, na-arụ ọrụ dị oke mkpa dị ka biosynthesis, nchekwa ike, na mkpochapụ ihe ndị na-emerụ ahụ. Nchegbu oxidative, nchịkọta nsí, na nsogbu nke metabolic bụ isi ihe na-akpata mmerụ imeju, imeju abụba abụba, na imeju fibrosis. Ihe bụ isi nke nchebe imeju, nbipu, na nrụgide antioxidative bụ iji nọgide na-arụ ọrụ hepatocyte, na-eme ka ọrụ enzyme na-emebi emebi, na ikpochapụ radicals n'efu. Peptide bekee, na ha elu ndu ọrụ na lekwasịrị kpọmkwem kpọmkwem, nwere ike kpọmkwem mezie hepatic metabolic ụzọ, na-echebe hepatocytes si oxidative mmebi, na-akwalite biotransformation na excretion nke toxins, apụta dị ka ọhụrụ ngwaọrụ maka igbochi na itinye aka na ọrịa imeju-gosipụta dị ịrịba ike na ọrịa imeju mmanya, ndị na-abụghị mmanya na-aba n'anya imeju ọrịa imeju (NAFLD) butere ọrịa imeju. GỤKWUO

Melanotan-2 (MT-2) bụ heptapeptide cyclic sịntetik na analọg nke α-melanocyte na-akpali akpali hormone (α-MSH). Ọ na-arụ ọrụ dị mkpa n'ịchịkwa melanocyte na-akpali ndị na-anabata homonụ. MT-2 na-arụ ọrụ nke ọma site na mmekọrịta ya na melanocortin 1 receptor (MC1R). A na-egosipụta MC1R n'ọtụtụ ebe n'elu melanocytes. Mgbe ejikọta ya na onye na-anabata ya, MT-2 na-amalite usoro nke ụzọ mgbaàmà intracellular, n'ikpeazụ na-akwalite njikọ na nkesa melanin, si otú ahụ na-eme mgbanwe na agba akpụkpọ ahụ. GỤKWUO

Site na mmepe nke sayensị ndụ na-aga n'ihu, nyocha n'ime usoro nke ịka nká na-abawanyewanye nke ọma, na ịchọta ụzọ mgbochi ịka nká nke ọma aghọwo isiokwu dị mkpa na mpaghara sayensị. Telomeres, dị ka ihe nchebe na njedebe nke chromosomes, nwere njikọ chiri anya na ịka nká cellular. Epitalon, peptide dị mkpụmkpụ sịntetị nwere mmetụta mgbochi ịka nká, dọtara uche n'afọ ndị na-adịbeghị anya. GỤKWUO

Nrụzi akwara na anụ ahụ bụ isi usoro physiological nke na-ejigide ọrụ moto, nguzozi n'ezi ihe, na nrụghachi ọrụ nke mmerụ ahụ gasịrị, gụnyere usoro mgbagwoju anya dị ka mmụba cell, extracellular matrix (ECM) remodeling, angiogenesis, na mkpali microenvironment ụkpụrụ. Ihe ndapụta dị mkpa na mpaghara a-gụnyere uto muscle, ọgwụgwọ ọnya, nrụzi nkwonkwo, na mgbake mmerụ egwuregwu-na-adabere na ntinye aka kpọmkwem na ntinye cell cell satịlaịtị, ọrụ fibroblast, cartilage matrix metabolism, na nrụzi nkwụsị nke neuromuscular. Ngwakọta peptide, yana ọrụ ndụ ha dị elu na ebumnuche ebumnuche ha, nwere ike gbanwee ụzọ akara ekwentị, kwalite nrụpụta anụ ahụ, na igbochi fibrosis, na-apụta dị ka ngwaọrụ dị oke mkpa iji merie ihe mgbakasị na usoro ọgwụgwọ ọdịnala na igosipụta atụmanya ngwa ngwa na ọgwụ egwuregwu, ịwa ahụ trauma, na ọgwụ na-emegharị ahụ. GỤKWUO

Ahụike ịmụ nwa bụ akụkụ dị mkpa nke ahụike mmadụ n'ozuzu ya, yana isi ya dabere na nguzozi na-arụ ọrụ nke usoro ọmụmụ n'okpuru ụkpụrụ hormonal. Usoro ahụike ịmụ nwa na usoro homonụ na-anọchite anya ọrụ etiti nke sistemu endocrine mmadụ, gụnyere usoro physiological isi dị ka mmepụta gamete, nguzozi nke homonụ mmekọahụ, mmezi ọmụmụ, na nhazi ọrụ mmekọahụ. Usoro ndị a na-adabere na njikwa ziri ezi nke hypothalamic-pituitary-gonadal (HPG) axis, na-agụnye njikọ ndị dị ka induction ovulation, nnọchi homonụ mmekọahụ, ọgwụgwọ ọmụmụ, na mgbanwe ọrụ mmekọahụ.  GỤKWUO