Los ntawm Cocer Peptides 
1 month ago
Tag nrho cov kab lus thiab cov ntaub ntawv ntawm cov khoom lag luam muab rau ntawm lub vev xaib no tsuas yog rau cov ntaub ntawv tshaj tawm kev tshaj tawm thiab cov hom phiaj kev kawm.
Cov khoom muab rau hauv lub vev xaib no yog npaj tshwj xeeb rau kev tshawb fawb hauv vitro. Kev tshawb fawb hauv vitro (Latin: * hauv iav *, lub ntsiab lus hauv iav) yog ua los ntawm tib neeg lub cev. Cov khoom no tsis yog tshuaj, tsis tau txais kev pom zoo los ntawm US Food and Drug Administration (FDA), thiab yuav tsum tsis txhob siv los tiv thaiv, kho, lossis kho txhua yam mob, kab mob, lossis mob. Nws raug txwv nruj raws li txoj cai los qhia cov khoom no rau hauv tib neeg lossis tsiaj lub cev hauv txhua daim ntawv.
Txheej txheem cej luam
Chronic nonbacterial prostatitis yog ib hom mob urological. Prostamax, tus neeg sawv cev kho tshiab cuam tshuam nrog bioactive peptides, ua lub luag haujlwm hauv kev tswj hwm kev noj qab haus huv ntawm prostate. Hauv kev kho mob ntawm kev sim mob ntev uas tsis yog kab mob prostatitis, Prostamax tau pom cov txiaj ntsig zoo.
Mechanism ntawm Action
Inflamation Regulation Mechanism: Inflammation is a key factor in development of chronic non-bacterial prostatitis. Prostamax zoo txo qhov mob ntawm qhov mob ntev, txo cov tsos mob xws li o, vascular congestion, thiab lymphoid infiltration. Cov nyhuv no tuaj yeem cuam tshuam nrog nws cov kev cai ntawm cov kab mob ntsig txog kev cuam tshuam. Nws tuaj yeem inhibit qhov kev tso tawm ntawm qee yam inflammatory yam tshwm sim los yog hloov kho cov chemotaxis thiab ua kom cov hlwb inflammatory, yog li txo qis cov lus teb hauv zos. Thaum mob, qee yam cytokines xws li qog necrosis factor-α (TNF-α) thiab interleukin-6 (IL-6) raug tso tawm ntau ntau, ua rau muaj qhov ua rau mob uas ua rau cov ntaub so ntswg puas thiab ua haujlwm tsis zoo. Prostamax tuaj yeem khi rau cov receptors tshwj xeeb ntawm lub xovtooj ntawm tes, qhib txoj hauv kev hauv lub cev, thiab inhibit qhov kev qhia thiab tso tawm ntawm cov teebmeem inflammatory, yog li txo cov tsos mob.
Table 1. Kev cuam tshuam ntawm cov tshuaj Prostamax ntawm qhov loj, ntim, thiab qhov ceev ntawm lub ventral feem ntawm lub caj pas prostate nyob rau hauv nas nrog mob aseptic o.
Cell tiv thaiv mechanism: Prostamax kuj muaj kev tiv thaiv kev loj hlob ntawm fibrosis thiab atrophy txheej txheem. Nyob rau hauv lub sij hawm ntev inflammatory stimulation, prostate cov ntaub so ntswg yog nquag mus rau ntau deposition ntawm extracellular matrix, ua rau cov ntaub so ntswg fibrosis thiab hardening, thaum lub hlwb kuj yuav raug atrophy vim yog yam xws li cov khoom noj tsis txaus thiab oxidative kev nyuaj siab. Prostamax tuaj yeem tswj hwm qhov qub morphology thiab kev ua haujlwm ntawm cov hlwb los ntawm kev txhawb nqa cov metabolism hauv cellular thiab txhawb kev muaj peev xwm antioxidant. Nws tuaj yeem txhim kho qhov kev qhia ntawm intracellular antioxidant enzymes xws li superoxide dismutase (SOD) thiab glutathione peroxidase (GSH-Px), tshem tawm cov pa oxygen ntau dhau (ROS) hauv cov hlwb, txo cov oxidative kev ntxhov siab vim cov cellular puas, thiab yog li tiv thaiv cellular atrophy thiab apoptosis. Nws kuj koom nrog hauv kev tswj cov synthesis thiab degradation tshuav nyiaj li cas ntawm extracellular matrix, inhibiting ntau synthesis ntawm fibrosis-txog cov proteins xws li collagen, thiab txhawb kev qhia ntawm matrix metalloproteinases (MMPs) kom tswj tau ib txwm extracellular matrix metabolism thiab tiv thaiv cov ntaub so ntswg fibrosis.
Hais txog kev sib deev muaj feem cuam tshuam txog kev tswj hwm txoj cai: Cov tshuaj no tuaj yeem txhim kho tus tsiaj txoj kev sib deev. Qhov kev cuam tshuam no cuam tshuam nrog nws cov kev cai ntawm kev tsim cov kab mob endocrine. Prostate, uas yog ib qho tseem ceeb ntawm cov txiv neej kev ua me nyuam system, muaj nws lub luag hauj lwm nyob rau hauv lub xeev uas muaj feem xyuam rau cov theem ntawm cov me nyuam cov tshuaj hormones. Prostamax tuaj yeem cuam tshuam rau kev tso tawm thiab kev ua haujlwm ntawm cov tshuaj hormones kev loj hlob xws li androgens los ntawm kev tswj hwm kev ua haujlwm ntawm hypothalamus-pituitary-gonadal axis. Nws txhawb kev tso tawm ntawm gonadotropin-tso cov tshuaj hormones (GnRH), uas nyob rau hauv lem ua rau lub caj pas pituitary secrete gonadotropins (LH thiab FSH), txhawb testosterone synthesis thiab secretion nyob rau hauv cov noob qes, yog li nce testosterone theem thiab pab kom tus tsiaj muaj peev xwm ua plees ua yi. Nws tuaj yeem ua ncaj qha rau ntawm cov leeg nqaij hauv cov qog nqaij hlav hauv prostate thiab cov plab hnyuv siab raum, tswj lawv cov kev cog lus thiab so kom txaus, txhim kho cov ntshav ncig hauv cov plab hnyuv siab raum, thiab muab lub cev zoo dua qub rau kev ua menyuam yaus.
Kev ua tau zoo
Txhim kho cov tsos mob inflammatory: Hauv kev kho mob ntev uas tsis yog kab mob prostatitis, Prostamax qhia tau hais tias muaj txiaj ntsig zoo hauv kev txo cov tsos mob inflammatory. Cov kev tshawb fawb tau pom tias tom qab kho nrog Prostamax, o ntawm cov nqaij mos prostate hauv cov tsiaj sim tau txo qis, vascular congestion tau txo qis, thiab lymphoid infiltration txo qis. Qhov no tsis yog tsuas yog txo qhov mob hauv zos, hnyav, thiab lwm yam tsos mob tsis xis nyob hauv cov neeg mob tab sis kuj tseem txhim kho microenvironment ntawm prostate hauv zos, tsim cov kev mob zoo rau cov ntaub so ntswg kho thiab rov tsim dua tshiab. Piv nrog rau cov tshuaj kho ib txwm siv, Prostamax tuaj yeem tswj tau qhov mob zoo dua, txo qhov kev puas tsuaj rau cov nqaij mos prostate los ntawm o, thiab txo qis kev pheej hmoo ntawm cov kab mob rov qab.
Txhim kho cov ntaub so ntswg prostate: Los ntawm kev tiv thaiv kev loj hlob ntawm fibrosis thiab atrophy, Prostamax pab tswj cov qauv thiab kev ua haujlwm ntawm cov ntaub so ntswg prostate. Fibrosis thiab atrophy ntawm cov ntaub so ntswg prostate tuaj yeem ua rau poob qis hauv nws cov kev ua haujlwm zais cia, cuam tshuam rau cov phev zoo thiab muaj pes tsawg leeg, thiab yog li cuam tshuam rau kev ua me nyuam. Prostamax tuaj yeem tiv thaiv cov kev hloov pauv pathological no los ntawm qhov tshwm sim, tswj hwm qhov qub morphology thiab cov qauv ntawm prostate acini thiab ducts, kom ntseeg tau tias prostate tuaj yeem tso cov kua dej hauv prostate, thiab tswj cov phev liquefaction thiab phev motility. Qhov no yog qhov tseem ceeb tshaj plaws rau cov neeg mob uas muaj mob prostatitis uas xav tau kev xeeb tub.
Table 2. Kev cuam tshuam ntawm cov tshuaj Prostamax ntawm morphometric indices ntawm lub caj pas prostate nyob rau hauv nas nrog mob prostatitis, % ntawm tus qauv cheeb tsam ntawm ib tug histological seem.
Txhim khu kev ua haujlwm ntawm kev ua me nyuam: Prostamax lub peev xwm los txhim kho kev sib deev hauv cov tsiaj tsis ncaj qha cuam tshuam nws qhov kev cuam tshuam zoo rau tag nrho kev ua haujlwm ntawm kev ua me nyuam. Hauv cov txiv neej kev noj qab haus huv, kev ua plees ua yi tsis yog cuam tshuam nrog kev ua haujlwm ntawm kev sib deev nws tus kheej nkaus xwb tab sis kuj tseem txuas nrog cov qib ntawm cov tshuaj hormones, cov ntshav ncig hauv cov plab hnyuv siab raum, thiab kev tswj hwm neural. Prostamax txhim kho txiv neej kev noj qab haus huv los ntawm kev tswj cov txheej txheem physiological. Nws tuaj yeem txhim kho cov ntshav muab rau cov penile corpus cavernosum, txhim khu kev ua haujlwm ntawm erectile, thiab kuj tseem tuaj yeem ua rau kom libido, txhawb kev ua me nyuam ib txwm muaj. Qhov no sawv cev rau kev kho thiab txhim kho txoj hauv kev rau cov neeg mob uas muaj kev sib deev tsis zoo los ntawm cov kab mob prostate.
Daim ntawv thov
Daim ntawv thov kev kho mob: Rau cov neeg mob uas mob me me uas tsis yog kab mob prostatitis, Prostamax tuaj yeem siv ib leeg rau kev kho mob, nrog cov tsos mob soj ntsuam kom txhim kho; rau cov mob me me mus rau qhov hnyav, nws tuaj yeem ua ke nrog cov tshuaj tua kab mob, alpha-receptor blockers, thiab lwm yam tshuaj rau kev kho mob kom ua tiav cov txiaj ntsig kho tau zoo dua. Thaum kho, cov kws kho mob tuaj yeem ntsuas qhov ua tau zoo ntawm Prostamax los ntawm kev kuaj xyuas cov kua dej prostate niaj hnub kuaj, prostate ultrasound, thiab lwm yam ntsuas, thiab kho cov phiaj xwm kho raws li xav tau.
Kev Tiv Thaiv Kev Noj Qab Haus Huv: Muab Prostamax cov kev tiv thaiv ntawm cov ntaub so ntswg prostate thiab nws cov kev cuam tshuam zoo rau kev ua haujlwm ntawm kev ua me nyuam, nws kuj muaj peev xwm tiv thaiv kev noj qab haus huv. Rau cov neeg muaj kev pheej hmoo siab rau cov kab mob prostate, xws li cov txiv neej laus lossis cov neeg uas muaj keeb kwm ntawm cov kab mob prostate, Prostamax tuaj yeem suav tias yog kev tiv thaiv kev noj qab haus huv ntxiv. Los ntawm kev noj cov tshuaj Prostamax hauv cov koob tshuaj me me rau lub sijhawm ntev, cov ntaub so ntswg kev noj qab haus huv tuaj yeem tswj tau, thiab qhov tshwm sim ntawm tus mob prostatitis, prostate hyperplasia, thiab lwm yam kab mob tuaj yeem tiv thaiv. Rau cov tib neeg uas muaj mob qog nqaij hlav me me tshwm sim los ntawm kev ua neej tsis zoo, xws li zaum ntev, haus cawv ntau dhau, lossis ua haujlwm dhau, Prostamax tuaj yeem siv los tswj thiab txhim kho prostate muaj nuj nqi, yog li txhim kho lub neej zoo. Thaum siv Prostamax rau kev tiv thaiv kev noj qab haus huv, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov nws txoj kev nyab xeeb thiab kev noj tshuaj kom tsim nyog, thiab nws yuav tsum tau siv raws li kev qhia ntawm tus kws kho mob lossis kws kho mob.
Daim duab 1 Sab feem ntawm cov nas prostate nrog mob prostatitis abacterial txais Prostamaks. Txo cov nqi ntawm collagen fibers piv rau kev tswj. Xim picrofuchsin. × 200.
Daim ntawv thov kev sib xyaw ua ke: Hauv kev kho mob ntawm cov kab mob prostate, cov tshuaj ib leeg feem ntau tsis ua tiav tag nrho cov teeb meem pathophysiological nyuaj. Prostamax tuaj yeem siv ua ke nrog lwm txoj kev kho mob kom ua tiav cov txiaj ntsig zoo. Thaum ua ke nrog kev kho lub cev xws li prostate massage lossis kho cua sov, nws tuaj yeem txhim kho cov ntshav ncig, txhim kho cov tshuaj nkag thiab nqus, thiab txhim kho kev kho mob.
Xaus
Raws li kev kho peptide tshiab, Prostamax qhia tau zoo hauv kev kho mob prostate. Los ntawm nws cov txheej txheem tshwj xeeb ntawm kev ua haujlwm rau nws cov txiaj ntsig tseem ceeb hauv kev txhim kho o, tswj cov ntaub so ntswg, thiab txhim kho kev ua haujlwm ntawm cov menyuam yaus, nrog rau nws txoj kev siv ntau yam hauv kev kho mob, kev tiv thaiv kev kho mob, thiab kev kho ua ke, nws pab txhawb kev kho thiab tiv thaiv kab mob prostate.
Qhov chaw
[1] Borovskaya TG, Pakhomova AV, Vychuzhanina AV, et al. Kev sim kawm txog kev siv tshuaj Prostamax hauv kev kho mob aseptic prostatitis ntev thiab nws cov teeb meem [J]. Kev tshawb fawb niaj hnub hauv kev mob ntsws, 2013,3(2):5.DOI:10.4236/mri.2013.23007.
Cov khoom muaj rau kev tshawb fawb siv nkaus xwb:
