Cocer Peptides ye ŋlɔe 
ŋkeke 15 enye sia
NYATAKAKAWO KPLE NUSIWO WOTSƆ ƑE NYATAKAKA SIWO KAtã WOÐO LE NYATAKAKADZRAÐOƑE SIA ME LA KPLE NYATAKAKAWO kaka KPLEE NUFIAFIA ƑE TAÐOÐOWO KO.
Wotrɔ asi le atike siwo wona le nyatakakadzraɖoƒe sia ŋu na numekuku le vitro ɖeɖeko. Wowɔa numekuku le vitro (Latingbe me: *le ahuhɔ̃e me*, si gɔmee nye le ahuhɔ̃e me) le amegbetɔ ƒe ŋutilã godo. Atike siawo menye atikewo o, United States ƒe Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) meda asi ɖe wo dzi o, eye mele be woazã wo atsɔ axe mɔ ɖe atikewɔwɔ, dɔléle, alo dɔléle aɖeke nu, adae, alo adae o. Se de se vevie be woatsɔ atike siawo ade amegbetɔ alo lãwo ƒe ŋutilã me le mɔ ɖesiaɖe nu.
BPC-157 ƒe wɔwɔfia
BPC-157 nye dɔgbo me pentapeptide si li ke si ŋu woke ɖo le gɔmedzedzea me le eƒe ŋutete si tsia abi nu ta. Enɔa amegbetɔ ƒe dɔgbo me tsi me gaƒoƒo 24 kple edzivɔ, si wɔnɛ be wòte ŋu wɔa eƒe ŋusẽkpɔɖeamedziwo le dɔgboa ƒe nɔnɔme me ɣesiaɣi eye wòɖoa gɔmeɖoanyi na dɔgbo kple ƒunukpeƒe siwo gblẽ la dzadzraɖo. Eƒe atikewo ƒe wɔwɔme
e nye GEPPPGKPADDAGLV, si ƒe molecule ƒe kpekpeme nye 1419. Molekyul ƒe wɔwɔme sia na wòte ŋu wɔa dɔ kple biomolecules vovovo siwo le ŋutilãa me, si wɔnɛ be wòwɔa ŋutilã me dɔ veviwo.
Nutata 1 BPC-157 kpɔa ŋusẽ ɖe HUVECwo ƒe dzidziɖedzi kple lãmenugbagbeviwo ƒe tsatsam ƒe mama dzi.
BPC-157 ƒe Dzadzraɖo ƒe Ŋusẽkpɔɖeamedzi ɖe Dɔgbo ƒe Nugbegblẽ Dzi
Dɔgbo ƒe Lãmenugbagbeviwo Takpɔkpɔ Kple Dɔgbo ƒe Fɔmaɖimaɖi Me léle Ðe Asi
BPC-157 wɔa akpa vevi aɖe le dɔgboa me lãmenugbagbeviwo takpɔkpɔ me, eye wòʋlia eta nyuie tso atike vovovowo ƒe nugbegblẽ le dɔgboa ŋu me. Zi geɖe la, nusiwo abe aha sesẽ kple atike siwo me steroid mele o (NSAIDs) gblẽa nu le dɔgboa ƒe lãmenugbagbeviwo ŋu eye wogblẽa dɔgboa ƒe blibonyenye me. BPC-157 ate ŋu akpɔ ƒodo me lãmenugbagbeviwo ta tso nusiwo gblẽa nu le ame ŋu siawo ƒe nugbegblẽ tẽ me to ŋutilã ƒe dɔwɔwɔ ƒe mɔnu sesẽ vovovowo dzi. Ne BPC-157 do go aha ƒe ʋuʋu la, eɖɔa lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe mɔnuwo ɖo le dɔgboa me lãmenugbagbeviwo me, enaa lãmenugbagbeviawo ƒe antioxidant defense system nyona ɖe edzi, eye wòɖea oxidative damage si aha ƒe metabolites hena vɛ dzi kpɔtɔna. Le dɔgbo ƒe lãkusi ƒe gbegblẽ si NSAID hena vɛ gome la, BPC-157 kpɔa ŋusẽ ɖe lãmenugbagbeviwo me dzesimɔwo dzi be wòaxe mɔ ɖe dɔdzẽ ƒe domenɔlawo ƒe dodo nu, si wɔnɛ be dɔdzẽ ƒe ŋuɖoɖowo ƒe nugbegblẽ le dɔgbo ƒe ʋukawo ŋu dzi ɖena kpɔtɔna. Esia kpena ɖe dɔgboa ƒe lãkusi ƒe blibonyenye ŋu eye wòkpɔa egbɔ be dɔgboa ƒe ŋutilã ƒe dɔwɔwɔ nyuie.
Nutata 2 BPC-157 dzi abi ƒe reepithelialization kple collagen ƒe agbɔsɔsɔ ɖe granulation tissue me ɖe edzi.
Dɔgbo ƒe gege ɖe lãme na ame ƒe liƒolili
Dɔgbo ƒe tsi ƒe gege ɖe lãme na ame ƒe dzidziɖedzi si mesɔ o nye nu vevi aɖe si nana dɔgbo me dɔléle geɖe va doa mo ɖa. Nusiwo doa dziku na dɔgboa, abe ŋutilã alo susu me nuteɖeamedzi, NSAID zazã, bile acid surfactant ƒe dzodzo, kple ahanono, katã ate ŋu ana dɔgboa ƒe lãkusiwo nate ŋu age ɖe lãme na ame geɖe wu, si ahe dɔgbo ƒe dɔléle si le dodom vɛ. BPC-157 ate ŋu ana dɔgboa ƒe ʋuʋu nali ke to protein siwo ƒoa ƒu sesĩe le dɔgboa ƒe lãmenugbagbevi siwo le dɔgboa me dome la dzi kpɔkpɔ me, si ana lãmenugbagbeviwo dome kadodo ƒe ŋusẽ nadzi ɖe edzi. Nyatakakawo ɖee fia be le lãwo ƒe kpɔɖeŋu siwo wotsɔ de nuteɖeamedzinu siwo míeyɔ va yi me la, BPC-157 zazã na protein siwo do ƒome kplikplikpli le dɔgboa ƒe lãmenugbagbevi siwo le dɔgboa me dome la ƒe ɖeɖefia dzi ɖe edzi, eye woƒe wɔwɔmewo le ɖoɖo nu sesĩe wu, si wɔe be dɔgboa ƒe gege ɖe molecule gãwo me dzi ɖe kpɔtɔ. Esia ɖe dɔgbo ƒe dɔléle si le dodom ƒe dzesiwo dzi kpɔtɔ nyuie, eɖe afɔku si le nusiwo gblẽa nu le ame ŋu ƒe gege ɖe ʋukawo me tso dɔgboa me dzi kpɔtɔ, eye wòna dɔgboa ƒe nuto suea li ke.
Dɔgbo kple dɔgbo ƒe abi ƒe dɔyɔyɔ dodo ɖe ŋgɔ
Eɖanye le abi siwo le dɔgboa me katã ƒe dɔyɔyɔ me alo gotagome ʋuʋudedi (abe nuɖuɖutome ŋutigbalẽ ƒe ʋuʋudedi, dɔgbo ƒe ŋutigbalẽ ƒe ʋuʋudedi, dɔgbo ƒe ŋutigbalẽ ƒe ʋuʋudedi, kple dɔgbo ƒe ŋutigbalẽ ƒe ʋuʋudedi) kple ememe ʋuʋudedi (abe dɔgbo ƒe tsinyegoe ƒe ʋuʋudedi kple dɔgbo ƒe nyɔnu ƒe ʋuʋudedi ene) le dɔgboa ƒe dɔwɔwɔ me o, BPC-157 ɖee fia nusiwo dona tso dodoɖeŋgɔ ƒe ŋusẽkpɔɖeamedzi ɖedzesiwo. BPC-157 doa fibroblasts ƒe dzidziɖedzi kple ʋuʋu ɖe ŋgɔ, enaa collagen ƒe wɔwɔme kple eƒe ƒuƒu kabakaba, to esia me naa matrix ƒe kpekpeɖeŋu si hiã hena abi ƒe dɔyɔyɔ. Eɖɔa nutoa me dɔdzẽ ƒe ŋuɖoɖowo hã ɖo, ehea dɔlélenutsiŋutete ƒe lãmenugbagbeviwo yia abi ƒe teƒea be woaɖe dɔlékuiwo kple lãmenugbagbevi siwo ku la ɖa, eye wòdoa ʋukawo ƒe dzɔdzɔ ɖe ŋgɔ, si wɔnɛ be nunyiame kple ɔksidzin sɔ gbɔ na abi la ƒe dɔyɔyɔ. Le dɔgbo ƒe anastomosis amekoko me la, ne anastomotic teƒea dze ŋgɔ dɔyɔyɔ ƒe kuxiwo le nusiwo abe NSAIDs, cystamine, alo colectomy ene ta la, BPC-157 ate ŋu awɔ akpa nyui aɖe hã le anastomotic dɔyɔyɔ dodo ɖe ŋgɔ me eye wòaɖe kuxiwo abe anastomotic fistula ene ƒe afɔkua dzi akpɔtɔ.
Ŋusẽkpɔɖeamedzi ɖe dɔgbo kple dɔgbo ƒe abiwo dzi
Le dɔgbo ƒe dɔléle sesẽ si ʋumenugbagbeviɣidɔ hena vɛ ƒe kpɔɖeŋu aɖe si wowɔ le sisiblisi me me la, BPC-157 ɖe ametakpɔkpɔ ƒe ŋusẽkpɔɖeamedzi fia ɖe dɔgboa ŋu eɖanye be wozãe abe mɔxexeɖedɔléle nu alo atike ene o. BPC-157 zazã atsɔ axe mɔ ɖe dɔlékuiwo nu ɖe dɔgbo ƒe dɔléle ƒe sesẽ dzi kpɔtɔ ŋutɔ, eɖe dɔgbo ƒe kuku, ʋuʋudedi, kple ʋumenugbagbevi dzĩwo ƒe gege ɖe lãme dzi kpɔtɔ, evɔ wòdzi monocyte ƒe xexlẽme ɖe edzi. Le dɔdzẽ sesẽ sesẽ si dzɔ xoxo dada me la, wokpɔ viɖe ɖedzesi aɖewo hã, eye wokpɔ amylase ƒe agbɔsɔsɔ si le ʋumenugbagbevi dzĩ me dzi. BPC-157 kpɔa ŋusẽ nyui ɖe dɔgbo kple dɔgbo ƒe abi siwo dzɔna le ɣeyiɣi ɖeka me hã dzi, si kpena ɖe ame ŋu be dɔgboa ƒe lãkusi ƒe blibonyenye nanɔ anyi eye wòɖea dɔdzẽ ƒe nugbegblẽ le dɔgboa kple dɔgbo ŋu dzi kpɔtɔna.
BPC-157 ƒe Dzadzraɖo ƒe Ŋusẽkpɔɖeamedzi ɖe Ƒunukpeƒewo ƒe Gbegblẽ Dzi
Temporomandibular ƒunukpeƒetetedɔ ƒe nyonyo
Le ƒunukpeƒetetedɔ ƒe kpɔɖeŋu si wowɔ le sisiblisi me la, wowɔ ƒunukpeƒetetedɔ ƒe ƒunukpeƒetetedɔ ƒe kpɔɖeŋu aɖe me la, wowɔ ƒunukpeƒetetedɔ ƒe nugbegblẽ, abe ƒunukpeƒetetedɔ ƒe akpa ɖeka ƒe ƒunukpeƒe ƒe gbegblẽ, ƒunukpeƒetetedɔ ƒe axadzi ƒe lãkusi si le axadzi, kple megbeƒu ƒe ƒunukpeƒetetedɔ ƒe dzidzeme ƒe lãɖeɖe ene, be woatsɔ awɔ ƒunukpeƒetetedɔ ƒe dɔléle ƒe ɖoɖoa ƒe kpɔɖeŋu. Le amekokoa megbe la, wodo BPC-157 to atike si wodona ɖe dɔgboa me dzi. Le ɣleti 6 ƒe kplɔkplɔ ɖo ƒe dodokpɔa me la, BPC-157 dɔdamɔnu ƒe ƒuƒoƒoa ɖe dzidziɖedzi gã aɖe fia le ƒunukpeƒe ƒe ƒunukpeƒe ƒe titrime bliboa me ne wotsɔe sɔ kple ƒuƒoƒo si me wokpɔa wo gbɔ le. Etɔxɛe la, esia dze abe ƒunukpeƒetetedɔ ƒe akpa si le ƒunukpeƒea kple ƒunukpeƒe siaa ƒe titrime dzi ɖe edzi, ƒunukpeƒea ƒe lãmenugbagbeviwo ƒe ƒuƒoƒo dzi ɖe kpɔtɔ, ƒunukpeƒea ƒe gbagbãƒe siwo le tsitrenu ƒe bu, kple ƒunukpeƒea ƒe ƒuƒoƒo si sɔ la takpɔkpɔ. Esia fia be BPC-157 ate ŋu aɖe temporomandibular joint osteoarthritis ƒe dɔléle ƒe tɔtrɔwo dzi akpɔtɔ nyuie eye wòado ƒunukpeƒetetedɔ ƒe dzadzraɖo kple eƒe gbugbɔgadzɔ ɖe ŋgɔ. Eƒe dɔwɔwɔ ƒe mɔnu ate ŋu ado ƒome kple BPC-157 ƒe kadodo kple molecule abe collagen kple proteoglycans siwo do ƒome kple ƒunukpeƒetetedɔ ƒe tsitsi. Le numekukuwo nu la, BPC-157 ƒe nɔnɔmetata geɖewo le collagen α-1 (I), collagen α-1 (IX), aggrecan, fibronectin ŋgɔdola, chondroitin sulfate proteoglycan NG2 ŋgɔdola, kple chondroitin oligosaccharide ŋgɔdola, siwo le vevie ŋutɔ na ƒunukpeƒe ƒe ƒunukpeƒe ƒe wɔwɔme kple dɔwɔwɔ me léle ɖe asi. BPC-157 ate ŋu ado ƒunukpeƒe ƒe ƒunukpeƒewo dzadzraɖo kple wo gbugbɔgatu ɖe ŋgɔ to molecule siawo ƒe ɖeɖefia alo woƒe dɔwɔwɔ dzi kpɔkpɔ me.
Nɔnɔmetata 3 BPC-157 do VEGF-a ƒe ɖeɖefia ɖe ŋgɔ le ŋutigbalẽ ƒe lãkusi siwo xɔ abi me.
Klo ƒe ƒunukpeƒe ƒe abixɔxɔwo dzadzraɖo
Klo ƒe ƒunukpeƒeveame nye dɔléle ƒe dzesi si bɔ si nu vovovowo hena vɛ, abe ƒunukpeƒetetedɔ, ƒunukpeƒetetedɔ, lãkusi ƒe dɔmawɔmawɔ nyuie, lãkusi ƒe vuvu, alo ƒunukpeƒetetedɔ ene. Numekuku aɖe si wowɔ le nusiwo dzɔ va yi ŋu la lé ŋku ɖe dɔnɔ 17 siwo ƒe klo ƒe ƒunukpeƒewo le veve sem ŋu, eye wokplɔ dɔnɔ 16 ɖo. Le dɔnɔ siawo dome la, wodo BPC-157 ɖeɖeko ɖe ʋuka me na ame 12, eye wo dometɔ 11 (91.6%) kpɔ ŋgɔyiyi gã aɖe le klo ƒe vevesese me; dɔnɔ 4 susɔeawo do BPC-157 kple thymosin-β4 ƒo ƒu, eye dɔnɔ siawo dometɔ 75% kpɔ vevesese dzi ɖe kpɔtɔ ŋutɔ. Le blibo me la, dɔnɔ 87.5% kpɔ klo ƒe vevesese dzi ɖe kpɔtɔ le BPC-157 alo eƒe kpeɖeŋutɔ kple thymosin-β4 zazã vɔ megbe. Esia ɖee fia be BPC-157 wɔa dɔ nyuie le klo ƒe vevesese ƒomevi vovovowo dzi ɖeɖe kpɔtɔ me. Numekuku bubuwo ɖee fia be ŋutete le BPC-157 ŋu be wòaɖɔ aɖatsiwo ɖo eye wòado ƒunukpeƒetetedɔ ƒe dzidzi ɖe ŋgɔ, si ate ŋu anye susu vevi aɖe si tae wòwɔa dɔ nyuie le klo ƒe vevesese dzi ɖeɖe kpɔtɔ me. Le ƒunukpeƒe ƒe abixɔxɔwo dzadzraɖo me la, BPC-157 ate ŋu ado ƒunukpeƒeŋusẽ ƒe dzidziɖedzi kple vovototodedeameme ɖe ŋgɔ, ana ƒunukpeƒetetedɔ ƒe wɔwɔme nadzi ɖe edzi, si ana ƒunukpeƒeŋusẽ ƒe lãkusi si gblẽ la naɖɔ ɖo. Tsɔ kpe ɖe eŋu la, ate ŋu awɔ dɔ ɖe lãkusi, lãkusi, kple lãkusi bubu siwo gblẽ hã dzi, si ana ƒunukpeƒewo nali ke nyuie wu eye wòaɖe vevesese si ƒunukpeƒewo ƒe malikenyenye hena vɛ dzi akpɔtɔ.
Abi siwo woxɔ le lãkusi kple lãmekawo ƒe kadodo ŋu dzadzraɖo
Esi woɖe ɖusime lãmeka si le sisiblisi me ƒe lãkusi ɖa tso lãmekaa gbɔ vɔ la, atikewɔwɔ kple BPC-157 ɖe atikewɔwɔ ƒe ŋusẽkpɔɖeamedzi ɖedzesiwo fia. Le nukpɔkpɔ gã aɖe me la, ƒuƒoƒo si me wokpɔa wo gbɔ la ɖe nɔnɔme madeamedzi gã aɖe fia le akɔta ƒe lãkusi kple lãmeka dome si yi edzi nɔ ŋgɔ yim, si wɔe be womete ŋu dɔyɔyɔ o. To vovo na ema la, sisiblisi siwo wotsɔ BPC-157 da dɔe la ɖe gbedada si yi edzi fia, eye nusi gblẽ le wo ŋu la le sue ŋutɔ tso gɔmedzedzea me, si na wogaɖo lãkusi kple lãmeka ƒe kadodo vevitɔ gbɔ mlɔeba. Nusuekpɔmɔ̃ me dodokpɔ ɖee fia be ƒuƒoƒo si me wokpɔa wo gbɔ la ɖe lãkusi ƒe ʋuʋu, ʋumenugbagbevi dzĩwo ƒe gege ɖe lãme na ame le mɔ si sɔ nu, kple lãmenugbagbevi siwo nye granulation ƒe wɔwɔme fia le kwasiɖa evelia me le amekokoa megbe, gake BPC-157 dɔdamɔnu ƒe ƒuƒoƒoa ya ɖe ʋumenugbagbeviɣi ƒe gege ɖe lãme fafɛ koe fia, granulation lãmenugbagbeviwo ƒe wɔwɔme aɖeke menɔ anyi o, eye lãkusi kple lãmeka ƒe kadodo ƒe wɔwɔme gbugbɔgaɖoanyi nyuie. Biomechanical assessment ɖee fia be lãmekawo ƒe ŋusẽ ƒe hayahaya menyo le ƒuƒoƒo si me wokpɔa wo gbɔ le me o, gake BPC-157 dɔdamɔnu ƒe ƒuƒoƒoa ya haya keŋkeŋ. Esia ɖee fia be menye ɖeko BPC-157 kpɔa ŋusẽ ɖe lãmeka kple lãkusi siwo xɔ abi dzi ko le atikewɔwɔ me ko o, ke eɖea ɖɔɖɔɖo kple atikewɔwɔ ƒe ŋusẽkpɔɖeamedzi tɔxɛwo hã fiana le nusiwo gblẽ le lãkusi kple lãmeka ƒe kadodo ŋu hã, si kpena ɖe ame ŋu be kadodo kple dɔwɔwɔ si sɔ la gaɖo lãmekawo kple lãkusiwo dome eye wònana ƒunukpeƒewo zɔna nyuie.
BPC-157 ƒe Ŋutete Kple Mɔkpɔkpɔwo le Dɔdamɔnu Zazã Me
Dɔgbomedɔlélewo Dada
Ne míebu BPC-157 ƒe ametakpɔkpɔ ƒe ŋusẽkpɔɖeamedzi ɖe dɔgbo ƒe lãmenugbagbeviwo dzi, dɔgbo ƒe gege ɖe lãme na ame ƒe liƒo, dɔgbo ƒe abi ƒe dɔyɔyɔ dodo ɖe ŋgɔ, kple ŋusẽ nyui si wòkpɔna ɖe dɔgboa kple dɔgbo ƒe abiwo dzi ta la, ŋutete gã aɖe le esi le dɔgbo ƒe dɔléle vovovowo dada me. Le dɔgbo me abi kple dɔgbo me abi dada me la, BPC-157 ate ŋu ana abi nahaya kabakaba eye wòaɖe afɔku si le eme be wòagadzɔ ake dzi akpɔtɔ. Le dɔgbo ƒe dɔléle siwo naa dɔdzẽ abe dɔgbo ƒe dɔléle ene gome la, BPC-157 ate ŋu ana dɔgboa ƒe ʋukawo ƒe mɔxenu ƒe dɔwɔwɔ nanyo ɖe edzi to dɔgboa ƒe dɔlélenutsiŋutete kple dɔdzẽ ƒe ŋuɖoɖowo dzi kpɔkpɔ me, aɖe dzesiwo dzi akpɔtɔ, eye wòado dɔlélea ƒe tsɔtsɔke ɖe ŋgɔ. Le dɔgbo ƒe dɔwɔwɔ vɔ megbe la, BPC-157 zazã ate ŋu akpe ɖe ame ŋu wòado anastomotic dɔyɔyɔ ɖe ŋgɔ, aɖe kuxiwo dzi akpɔtɔ, eye wòana dɔnɔa nahaya kabakaba.
Ƒunukpeƒedɔlélewo dada
Le ƒunukpeƒedɔlélewo gome la, BPC-157 ƒe ɖɔɖɔɖo ƒe ŋusẽkpɔɖeamedzi ɖe ƒunukpeƒetetedɔ kple klo ƒe abixɔxɔ dzi naa gɔmesese yeyewo le eŋu le alesi wòate ŋu azãe le ƒunukpeƒetetedɔ kple kamedefefe ƒe abi dada me ŋu. Le ƒunukpeƒetetedɔlélawo gome la, BPC-157 ate ŋu anye atike si ate ŋu atrɔ dɔlélea, menye ɖeko wòaɖe vevesese ƒe dzesiwo dzi akpɔtɔ ko o, ke ana ƒunukpeƒetetedɔ hã nagbɔdzɔ, ana ƒunukpeƒewo naɖɔ ɖo, eye wòana ƒunukpeƒewo nawɔ dɔ nyuie wu. Le kamedefefe me abi siwo woxɔna, abe lãkusi kple lãkusi ƒe abi siwo woxɔna le klo kple afɔkpodzi ƒe ƒunukpeƒewo si wokpɔna zi geɖe le kamedefefewɔlawo ŋu ene, dada me la, BPC-157 ate ŋu ana lãmeka siwo gblẽ la ɖɔɖɔɖo kabakaba, ana ɣeyiɣi si woatsɔ aɖɔe ɖo la nadidi, eye wòana kamedefefewɔlawo ƒe kamedefefe ƒe ŋutete nahaya kabakaba.
Nyanuwuwuw
Abe peptide si wɔa dɔ le nugbagbewo me si wɔa nuwo ɖɔɖɔɖodɔ geɖe ene la, BPC-157 ɖea dɔwɔwɔ aɖewo fiana le dɔgbo kple ƒunukpeƒe ƒe abi dzadzraɖo ƒe akpawo me.
Dzɔtsoƒewo
[1] Lee E, Padgett B J. Intra-Articular Injection of BPC 157 na Klo Vevesese Ƒomevi Geɖe.[J]. Atikewɔwɔ Bubuwo le Lãmesẽ kple Atikewɔwɔ me, 2021,27 4:8-13.DOI:https://api.semanticscholar.org/CorpusID:236516759.
[2] Sikiric P, Drmic D, Sever M, kple ame bubuwo. Fistulas ƒe Dɔyɔyɔ. Dɔgbo me Pentadecapeptide si Li ke BPC 157 Atikewɔwɔ[J]. Fifia ƒe Atikewɔwɔ ƒe Aɖaŋu, 2020,26 (25): 2991-3000.DOI: 10.2174/ 13816128266 66200424180139.
[3] Sikiric P, Hahm KB, Blagaic A. B., kple ame bubuwo. Stable Gastric Pentadecapeptide BPC 157, Robert ƒe Dɔgbo ƒe Lãmenugbagbeviwo Takpɔkpɔ/Adaptive Cytoprotection/Organoprotection, kple Selye ƒe Nuteɖeamedzi Dziɖuɖu ƒe Ŋuɖoɖo: Ŋgɔyiyi, Dzidzedzekpɔkpɔwo, Kple Etsɔme[J]. Dɔgbo kple aklã, 2020, 14 (2): 153-167.DOI: 10.5009 / gnl18490.
[4] Huang T, Zhang K, Sun L, kple ame bubuwo. Ŋutilã takpɔnu-157 doa ŋusẽ abi ƒe dɔyɔyɔ le alkali-fiã me le vivo eye wòdoa dzidziɖedzi, ʋuʋu, kple ʋukawo ƒe dzɔdzɔ ɖe ŋgɔ le vitro[J]. Atike Des Devel Ther, 2015, 9: 2485-2499.DOI: 10.2147 / DDDT.S82030.
[5] Kokic N, Sikiric P, Seiwerth S, kple ame bubuwo. Pentadecapeptide BPC-157 kple sisiblisi ƒe ƒunukpeƒe ƒe ƒunukpeƒetetedɔ[M]. 2001.https://www.researchgate.net/publication/266736896_Pentadecapeptide_BPC-157_kple_rat_temporomandibular_ƒunukpeƒetetedɔ.
[6] Sikirić P, Seiwerth S, Grabarević Z, kple ame bubuwo. Pentadecapeptide BPC 157 ƒe dɔyɔyɔ kple mɔxexeɖedɔléle nu ƒe ŋusẽkpɔɖeamedzi ɖe dɔgbo ƒe dɔléle sesẽ kple dɔgbo ƒe abi siwo kpe ɖe eŋu le sisiblisiwo me dzi[J]. Nuɖuɖumeŋusẽdɔlélewo kple Dzɔdzɔmeŋutinunya, 1996, 41 (7): 1518-1526.DOI: 10.1007 / BF02088582.
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