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1kits (10Vials) .
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▎ CJC1295 DAC ƒe Dɔwɔɖoɖo aɖeke meli o
Dzɔtsoƒe: PubChem |
Nusiwo woɖo ɖe wo nɔewo yome: YADAXFXQSYRKVLAQLSARKLLQDXLSR Molekyulãwo ƒe Mɔfiame: C 152H 252N 44O42 Molekyulã ƒe Kpekpeme: 3367.9g/mol CAS ƒe xexlẽdzesi: 446262-90-4 PubChem ƒe CID: 91976842 |
▎ CJC1295 DAC ƒe Numekuku aɖeke meli o
Nukae nye numekuku ƒe megbenyawo le CJC1295 no DAC ŋu?
Wozãa tsitsi ƒe lãmetsiŋusẽ (GHRH) le atikewɔwɔ me be wòana tsitsi ƒe lãmetsi (GH) ƒe dodo nadzi ɖe edzi, gake seɖoƒe gã aɖe le eŋu, si nye eƒe dɔwɔwɔ ɣeyiɣi kpui aɖe [1] . Esia xea mɔ na GHRH zazã le atikewɔnyawo me le afisiafi eye wòʋãa numekulawo be woadi atike bubu siwo wɔa dɔ ɣeyiɣi didi wu. CJC1295 no DAC nye peptide atike si wotu ɖe amino acid 30 dzi. Ate ŋu aʋã lãkusi si le lãkusia me be wòaɖe tsitsiŋusẽ (GH) ɖa. Peptide-tike sia to vovo na peptide-tike xoxowo. Eƒe etɔxɛnyenye le maleimide propionic acid ƒe ƒuƒoƒo si wɔa dɔ ƒe anyinɔnɔ me, si ate ŋu abla ɖe thiol siwo le ablɔɖe me le plasma proteinwo ƒe anyime le covalent me. Ne wonya bla ɖe plasma proteinwo ŋu ko la, CJC1295 no DAC le ʋu me ƒe dɔwɔwɔ ƒe ɣeyiɣi didi ŋutɔ. Ne wotsɔe sɔ kple peptide-tike siwo womebla o la, peptide-tike mawo siwo womebla o la ado le ŋutilãa me kabakaba, evɔ CJC1295 no DAC si wobla la ya ate ŋu anɔ dɔ wɔm le ʋua me ɣeyiɣi didi wu. Mɔnu sia si blaa nu na CJC1295 no DAC nye atike si wɔa dɔ tɔxɛ aɖe.
Nukae nye CJC1295 no DAC ƒe dɔwɔwɔ ƒe mɔnu?
Dɔlékuiwutikea ƒe ʋuʋu be wòaɖe tsitsi ƒe lãmetsiŋusẽ ɖa: Atike sia ate ŋu aʋã ʋuka si me ʋu sina tona be wòaɖe tsitsiŋusẽ (GH) ɖa. Ne CJC1295 DAC aɖeke mege ɖe ŋutilãa me o la, ewɔa dɔ ɖe lãkusia dzi to mɔnu aɖe koŋ dzi, si wɔnɛ be lãkusi me lãmenugbagbeviwo dzia GH ƒe dodo ɖe edzi. Etɔxɛe la, ate ŋu abla ɖe lãmenugbagbevi tɔxɛ siwo le lãkusi me lãmenugbagbeviwo ƒe anyime ŋu, si adze dzesiwo ƒe tɔtrɔmɔ vovovowo gɔme, si ana GH ƒe wɔwɔme kple eƒe dodo nadzi ɖe edzi mlɔeba [1, 2]..
Nusiwo blana ɖe plasma proteinwo ŋu: CJC1295 no DAC ƒe nɔnɔme tɔxɛ aɖe le esi, si fia be ƒuƒoƒo aɖe si wɔa dɔ le eƒe wɔwɔme me, si ate ŋu abla ɖe thiol siwo le ablɔɖe me le plasma proteinwo ƒe anyime ŋu le covalent me. Kpekpeɖeŋu sia nana ɣeyiɣi si atike la nɔa dɔ wɔm le ʋua me la didi ŋutɔ. Ne wotsɔe sɔ kple peptide atike siwo womebla o la, CJC1295 no DAC si wobla la ƒe afã ƒe agbenɔƒe didi wu [2] . Numekuku aɖewo ɖee fia be CJC-1295 dea maleimide ƒuƒoƒo si wɔa dɔ le C-nuwuƒe, si wɔnɛ be wòte ŋu blana ɖe plasma proteinwo abe serum albumin ene ŋu le covalent me. Ne wonya blae ko la, ateŋu aʋã GH wɔwɔ le amegbetɔwo me wu ŋkeke ade le edodo zi ɖeka megbe (Timms M, 2019, a).
Tsitsi ƒe lãmetsi ƒe dodo dzi ɖeɖe kpɔtɔ: Ne wodo CJC1295 no DAC zi ɖeka vɔ la, ana GH ƒe agbɔsɔsɔ si le ʋumenugbagbevi dzĩ me le mama dedie nu nadzi ɖe edzi le agbɔsɔsɔme si wozã nu. Dzidziɖedzi sia ate ŋu anɔ anyi ŋkeke 6 alo esi wu nenema, eye dzidziɖedzia ƒe didime anɔ zi gbɔ zi 2 va ɖo zi gbɔ zi 10 [2-4] . Le numekuku aɖe me la, esi wodo CJC-1295 ɖe ŋutigbalẽ te na ame tsitsi siwo le lãmesẽ me vɔ la, GH ƒe agbɔsɔsɔ dzi ɖe edzi atraɖii, si nɔ te ɖe agbɔsɔsɔme si wozã dzi. CJC-1295 ƒe afã ƒe agbenɔƒe si wobu be enye ŋkeke 5.8 - 8.1 (Teichman SL, 2006). Le GHRH knockout (GHRHKO) mice hã me la, woɖe nɔnɔme mawo tɔgbe fia. CJC1295 dodo gbesiagbe ate ŋu alé ŋutilã ƒe wɔwɔme kple tsitsi si sɔ ɖe te [5]..
Ŋusẽkpɔɖeamedzi ɖe tsitsinu I si le abe insulin ene ƒe dodo dzi: CJC1295 DAC aɖeke makpɔ ŋusẽ ɖe tsitsinu si le abe insulin ene I (IGF-I) ƒe dodo hã dzi. IGF-I ƒe agbɔsɔsɔ le ʋumenugbagbevi dzĩ me le mama dedie nu adzi ɖe edzi le mɔ si anɔ te ɖe agbɔsɔsɔme si wozã dzi, eye wòadzi ɖe edzi zi gbɔ zi 1.5 va ɖo zi 3, eye ɣeyiɣi didi si wòaxɔ la anye ŋkeke 9 - 11 [2-4] . Le CJC1295 no DAC ƒe agbɔsɔsɔme dodo zi geɖe megbe la, IGF-I ƒe agbɔsɔsɔ le mama dedie nu nɔa kɔkɔm wu gɔmedzedze ƒe agbɔsɔsɔme vaseɖe ŋkeke 28 (Teichman SL, 2006). Le GHRHKO mice me la, CJC1295 hã na pituitary RNA bliboa kple GH mRNA dzi ɖe edzi, si fia be lãmenugbagbevi siwo ɖea tsitsi ƒe lãmetsiwo ɖe go la dzina ɖe edzi [5]..
CJC-1295 ƒe plasma bu ƒe fliwo le sc dodo zi ɖeka megbe. Woɖe SD ƒe agbenɔƒe afã le mama dedie nu fia.
Dzɔtsoƒe:PubMed [1] .
Vovototo kawoe le CJC1295 no DAC ƒe atikewɔwɔmɔnu me na dɔnɔ siwo ƒe tsitsime lãmetsiŋusẽ ƒe dɔmawɔmawɔ nyuie le ƒe vovovowo me?
Ðevi dɔnɔwo: Ðeviwo le tsitsi kple tsitsi ƒe ɣeyiɣi vevi aɖe me, eye tsitsi ƒe lãmetsi wɔa akpa vevi aɖe le woƒe ƒuwo, lãmekawo, kple ŋutinuwo ƒe tsitsi kple tsitsi me. Tsitsi ƒe lãmetsiŋusẽ ƒe anyimanɔmanɔ ate ŋu ahe kuxiwo abe tsitsi blewu, kɔkɔme kpui, kple ƒu ƒe tsitsi si tsi megbe ene vɛ na ɖeviwo.
CJC1295 no DAC doa ɖeviwo ƒe tsitsi kple tsitsi ɖe ŋgɔ to alesi wòʋãa pituitary gland be wòaɖe tsitsi ƒe lãmetsiŋusẽ ɖa. Ate ŋu ana tsitsi ƒe lãmetsi ƒe dodo kple ɣeyiɣi didi nadzi ɖe edzi, eye wòana tsitsi ƒe lãmetsi kple insulin-like growth factor - I (IGF-I) ƒe agbɔsɔsɔ nadzi ɖe edzi le ʋumenugbagbeviɣi me [3] . IGF-I ye nye domenɔla vevitɔ na tsitsiŋusẽ ƒe dɔwɔwɔ. Ate ŋu ado lãmenugbagbeviwo ƒe dzidziɖedzi, vovototodedeameme, kple protein ƒe wɔwɔme ɖe ŋgɔ, eye wòwɔa akpa vevi aɖe le ƒuwo, lãmekawo, kple ŋutinuwo ƒe tsitsi kple tsitsi me. CJC1295 no DAC ateŋu ado ƒu ƒe asitɔtrɔ ƒe dzesiwo abe osteocalcin kple alkaline phosphatase ene ƒe dzidziɖedzi hã ɖe ŋgɔ, si kpena ɖe ƒuwo ƒe tsitsi kple mineralization ŋu. Tsɔ kpe ɖe eŋu la, CJC1295 no DAC mekpɔa ŋusẽ aɖeke si dze ƒã ɖe lãkusi ƒe dɔwɔwɔ dzi o eye dedienɔnɔ ƒe seƒe gã aɖe le esi.
Dɔnɔ tsitsiwo:
Dɔnɔ tsitsi siwo ƒe tsitsimeŋusẽ ƒe dɔmawɔmawɔ nyuie ate ŋu ado go kuxiwo abe lãmekawo ƒe dzidziɖedzi, ami ƒe dzidziɖedzi, ŋutilã ƒe ŋusẽ dzi ɖeɖe kpɔtɔ, dzitodzito me dɔlélewo ƒe afɔku si dzi ɖe edzi, kple ƒumeŋuɖui ene. Ne wotsɔe sɔ kple ɖevi dɔnɔwo la, wowu dɔnɔ tsitsiwo ƒe tsitsi kple tsitsi nu koŋ, eye atikewɔwɔ ƒe taɖodzinue nye be woana lãmenugbagbeviwo ƒe dɔwɔwɔ kple agbenɔnɔ ƒe nyonyome nanyo ɖe edzi. CJC1295 no DAC ƒe dɔdamɔnu si wozãna le dɔnɔ tsitsiwo me koŋue nye be wòana lãmekawo ƒe ŋusẽ nanyo ɖe edzi, aɖe ami ƒe agbɔsɔsɔ dzi akpɔtɔ, ana dzi ƒe dɔwɔwɔ nanyo ɖe edzi, ahe tsitsi ɖe megbe, eye wòaxe mɔ ɖe ƒumeŋuɖui nu to tsitsi ƒe lãmetsi kple IGF-I ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ me. Numekukuwo ɖee fia be CJC1295 no DAC ate ŋu ana dɔnɔ tsitsiwo ƒe ŋutilã ƒe lolome nadzi ɖe edzi, aɖe ami si le ŋutigbalẽ te dzi akpɔtɔ, ana insulin ƒe dɔwɔwɔ nanyo ɖe edzi, eye wòaɖe dzitodzito me dɔlélewo ƒe afɔkua dzi akpɔtɔ. Tsɔ kpe ɖe eŋu la, CJC1295 no DAC ate ŋu ado ƒuwo ƒe tsitsi kple mineralization hã ɖe ŋgɔ, ana ƒu ƒe kpekpeme nadzi ɖe edzi, eye wòaxe mɔ ɖe ƒumeŋuɖui nu [3, 5]..
Dɔnɔ tsitsiwo:
Ne ame tsi la, tsitsi ƒe lãmetsi si dona le amegbetɔ ƒe ŋutilã me dzi ɖena kpɔtɔna vivivi, si wɔnɛ be kuxiwo abe lãmekawo ƒe lolome dzi ɖena kpɔtɔna, ami ƒe dzidziɖedzi, ƒumeŋuɖui, kple dɔlélenutsiŋutete dzi ɖena kpɔtɔna ene. Dɔnɔ tsitsi siwo ŋu tsitsimeŋusẽ ƒe dɔmawɔmawɔ nyuie le la ate ŋu axɔ dɔlélea wu, eye atikewɔwɔa sesẽna wu. CJC1295 no DAC ƒe atikewɔwɔmɔnu le dɔnɔ tsitsiwo me sɔ kple esi le dɔnɔ tsitsiwo gome, gake ele be woatrɔ asi le agbɔsɔsɔme si wozãna ŋu nyuie wu eye ele be woalé ŋku ɖe eƒe nugbegblẽ le ame ŋu ŋu. Le dɔnɔ tsitsiwo ƒe ŋutilã ƒe dɔwɔwɔ dzi ɖeɖe kpɔtɔ kple ŋutete si le wo si be woatrɔ asi le atikewo ŋu ahaɖe wo ɖa ta la, ehiã be woaɖe atikeawo ƒe agbɔsɔsɔ dzi akpɔtɔ be woaƒo asa na atikewo ƒe ƒuƒoƒo kple nu gbegblẽ siwo dona tso eme.
Numekuku siwo do ƒome kplii
Nukae nye CJC1295 no DAC ƒe ŋusẽkpɔɖeamedzi?
Tsitsi ƒe lãmetsi ƒe dodo ɖe ŋgɔ:
Abe tsitsiŋusẽ ƒe lãmetsiŋusẽ (GHRH) ƒe kpɔɖeŋu ene la, CJC1295 DAC aɖeke mate ŋu abla ɖe GHRH xɔla siwo le ŋgɔgbe lãkusi me eye wòaʋã tsitsi ƒe lãmetsiŋusẽ ƒe wɔwɔme kple eƒe dodo to tsitsi ƒe lãmetsiŋusẽ ƒe lãmenugbagbeviwo me o. Tsitsi ƒe lãmetsi le vevie ŋutɔ na ŋutilã ƒe tsitsi kple tsitsi, lãmenugbagbeviwo ƒe dɔwɔwɔ, kple lãmenugbagbeviwo ɖɔɖɔɖo ƒe ɖoɖowo. Le numekuku aɖewo me la, ne wozã CJC1295 no DAC vɔ la, woate ŋu akpɔ tsitsiŋusẽ ƒe agbɔsɔsɔ si le ʋu me ƒe dzidziɖedzi, si kpena ɖe ame ŋu be lãmekawo abe ƒuwo kple lãmekawo ene ƒe tsitsi kple wo dzadzraɖo ɖe ŋgɔ.
Lãmetsiŋusẽ ƒe dɔwɔwɔ dzi kpɔkpɔ:
Tsitsi ƒe lãmetsi wɔa akpa vevi aɖe le lãmenugbagbeviwo ƒe dɔwɔwɔ dzi kpɔkpɔ me. CJC1295 no DAC kpɔa ŋusẽ ɖe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi le mɔ si mele tẽ o nu to tsitsi ƒe lãmetsi ƒe dodo ɖe ŋgɔ me. Ate ŋu ado ami ƒe gbagbã ɖe ŋgɔ, si ana woazã ami abe ŋusẽtsoƒe ene, si kpena ɖe ame ŋu be ami ƒe dzadzraɖo ɖe ŋutilãa me dzi naɖe akpɔtɔ eye wòana ami ƒe mama nanyo ɖe edzi le ŋutilãa me. Le ɣeyiɣi ma ke me la, ate ŋu ado protein ƒe wɔwɔme hã ɖe ŋgɔ, ana protein ƒe sisi ɖe lãmekawo me nadzi ɖe edzi, si kpena ɖe lãmekawo ƒe nyonyome kple ŋusẽ ŋu, eye wòana ŋutilãa ƒe kamedede ƒe ŋutete kple dzidodo nanyo ɖe edzi. Tsɔ kpe ɖe eŋu la, CJC1295 no DAC hã kpɔa ŋusẽ aɖe ɖe sukli ƒe asitɔtrɔ dzi, eye ate ŋu ana insulin ƒe dɔwɔwɔ nadzi ɖe edzi, si kpena ɖe ame ŋu be sukli ƒe agbɔsɔsɔ si sɔ le ʋu me nanɔ anyi.
Lãmetsiŋusẽwo dzadzraɖo kple wo gbugbɔgadzɔ dodo ɖe ŋgɔ:
Tsitsi ƒe lãmetsi wɔa akpa vevi aɖe le lãkusi siwo gblẽ la dzadzraɖo kple wo gbugbɔgawɔ me. CJC1295 no DAC doa tsitsi ƒe lãmetsiŋusẽ ƒe dodo ɖe ŋgɔ, si hã doa ŋusẽ lãmenugbagbeviwo ƒe dzidziɖedzi kple vovototodedeameme, enaa abi ƒe dɔyɔyɔ kabakaba, eye wòdoa lãkusi siwo gblẽ la dzadzraɖo ɖe ŋgɔ. Le dodokpɔ aɖewo siwo wowɔ le lãwo ŋu kple dɔdamɔnu ŋuti numekuku aɖewo me la, wokpɔe be ekpena ɖe ame ŋu le lãmekawo ƒe gbagbã ƒe dɔyɔyɔ, lãmekawo ƒe abi dzadzraɖo, kple ŋutigbalẽ ƒe abi ƒe dɔyɔyɔ, kple bubuawo me, eye wòate ŋu anye vevienyenye si ana ŋutilãa ƒe hayahaya ŋutete nanyo ɖe edzi eye wòana lãmeka siwo gblẽ la nawɔ dɔ ake.
Nukae nye CJC1295 no DAC ƒe dɔwɔwɔ ƒe akpawo?
Tsitsi ƒe lãmetsiŋusẽ ƒe anyimanɔmanɔ ƒe atikewɔwɔ:
Le dɔnɔ siwo ƒe tsitsime lãmetsiŋusẽ mesɔ gbɔ o gome la, CJC-1295 DAC manɔmee ate ŋu ana tsitsi ƒe lãmetsi ƒe dodo, si ana ŋutilãa natsi ahatsi. Ate ŋu ana atikewɔmɔnu yeye na dɔnɔ mawo siwo mewɔa dɔ nyuie le tsitsimeŋusẽ ƒe atikewɔwɔ si wozãna tsã ŋu o [3]..
Lãmetsiŋusẽ ƒe dɔlélewo dzi kpɔkpɔ:
Tsitsi ƒe lãmetsi wɔa akpa vevi aɖe le ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi kpɔkpɔ me. CJC-1295 DAC manɔmee ate ŋu ana insulin ƒe dɔlélenutsiŋutete nanyo ɖe edzi, aɖɔ ami ƒe asitɔtrɔ ɖo, kple bubuawo to tsitsi ƒe lãmetsi ƒe dodo dzi ɖeɖe kpɔtɔ me, eye ate ŋu anye atikewɔwɔ ƒe ŋutete aɖewo na lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe kuxiwo abe suklidɔ kple lolo akpa ene [3]..
Ŋutilã ƒe ɖekakpuiwɔwɔ:
Tsitsi ƒe lãmetsi ate ŋu ado kolagen ƒe wɔwɔme ɖe ŋgɔ, ana ŋutigbalẽa nate ŋu asẽ ɖe edzi, eye wòaɖe flitete dzi akpɔtɔ. CJC-1295 DAC manɔmee ate ŋu ana ŋutigbalẽ nazu ɖekakpui to tsitsi ƒe lãmetsi ƒe dodo me [6]..
Ŋutilã ƒe dɔwɔwɔ nyuie wu:
Ne ame le tsitsim la, ŋutilãa ƒe dɔwɔwɔ vovovowo dzi aɖe akpɔtɔ vivivi. Tsitsi ƒe lãmetsi ate ŋu ana lãmekawo ƒe ŋusẽ nadzi ɖe edzi, ana ƒu ƒe kpekpeme nanyo ɖe edzi, eye wòana dɔlélenutsiŋutete nanyo ɖe edzi, kple bubuawo CJC-1295 DAC manɔmee ate ŋu akpe ɖe ame ŋu be wòahe tsitsi ƒe ɖoɖoa ɖe megbe eye wòana ame tsitsiwo ƒe agbenɔnɔ nanyo ɖe edzi [3]..
Lãmetsiwo ƒe ŋusẽ dzi ɖeɖe kpɔtɔ:
Tsitsi ƒe lãmetsi ate ŋu ado protein ƒe wɔwɔme ɖe ŋgɔ eye wòana lãmekawo nadzi ɖe edzi. Le kamedefefewɔlawo kple kamedede lɔ̃lawo gome la, CJC-1295 DAC manɔmee ate ŋu akpe ɖe ame ŋu be lãmekawo ƒe ŋusẽ kple dzidodo nanyo ɖe edzi [6]..
Kamedede ƒe hayahaya dodo ɖe ŋgɔ:
Le kamedede sesẽ megbe la, ŋutilãa hiãa ɣeyiɣi hafi wòahaya. Tsitsi ƒe lãmetsi ate ŋu ana lãmenugbagbevi siwo gblẽ la naɖɔ ɖo kabakaba eye wòaɖe dɔdzẽ ƒe dɔwɔwɔ dzi akpɔtɔ. CJC-1295 DAC manɔmee ate ŋu akpe ɖe ame ŋu be ɣeyiɣi si woatsɔ ahaya le kamedede megbe la nanɔ kpuie eye wòana kamedede ƒe ŋutete nanyo ɖe edzi [3]..
Tsitretsitsi ɖe tsitsi ŋu:
Esi amewo le ŋku lém ɖe tsitsi nutsitsi ŋu geɖe wu ta la, ame aɖewo hã bua CJC1295 no DAC be ŋutete le esi be wòatsi tsitsi nu. Tsitsi ƒe lãmetsi kple IGF-I wɔa akpa vevi aɖe le ŋutilã ƒe ŋutilã ƒe dɔwɔwɔ nyuie kple lãmenugbagbeviwo ɖɔɖɔɖo me. Eyata nu sia ate ŋu akpɔ ŋusẽ ɖe tsitsi ƒe ɖoɖoa dzi to nu siawo dzi kpɔkpɔ me [3]..
Abe lãmetsi si ɖea tsitsi ƒe lãmetsiwo ƒe kpɔɖeŋu ene la, CJC1295 no DAC mekpɔa ŋusẽ ɖe ame dzi vevie o. Ate ŋu aʋã ʋuka si me ʋu sina tona be wòaɖe tsitsi ƒe lãmetsiŋusẽ ɖa, aɖɔ tsitsinu I si le abe insulin ene ƒe dodo ɖo, eye wòato esia me akpɔ ŋusẽ ɖe ŋutilãa ƒe tsitsi kple eƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi. Le dzɔdzɔmeŋutinunya me numekukuwo me la, enaa kpekpeɖeŋu vevi aɖe le alesi tsitsiŋusẽ ƒe dɔwɔwɔ wɔa dɔe me dzodzro me eye wòdoa nufiafia siwo sɔ ƒe ŋgɔyiyi ɖe ŋgɔ. Le dɔdaƒewo zazã me la, le dɔnɔ siwo ƒe tsitsimeŋusẽ mesɔ gbɔ o gome la, wokpɔa mɔ be aʋã tsitsimeŋusẽ si le lãmenugbagbeviwo me ƒe dodo eye wòana tsitsi kple tsitsi kpakple lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe tɔtrɔwo nanyo ɖe edzi. Eɖe ŋutete si le eŋu hã be wòaɖɔ lãmetsiŋusẽ ƒe agbɔsɔsɔ ɖo eye wòawɔ avu kple tsitsi ƒe tɔtrɔ le numekuku siwo wowɔ tsɔ tsi tre ɖe tsitsi ŋu me. Le nusianu me la, ele vevie ŋutɔ le dzɔdzɔmeŋutinunya me numekuku kple dɔdamɔnu siaa me, si hea mɔnukpɔkpɔ yeyewo vɛ na numekuku siwo do ƒome kplii kple dɔlélewo dada.
Le Agbalẽŋlɔla La Ŋu
Nusiwo míeyɔ ɖe etame la katã nye esiwo ŋu Cocer Peptides wɔ numekuku le, trɔ asi le wo ŋu eye woƒo wo nu ƒu.
Dzɔdzɔmeŋutinunya ƒe Agbalẽŋlɔla
Teichman SL nye eŋutinunyala si si nuteƒekpɔkpɔ geɖe le eye wòkpɔ ŋusẽ ɖe atikewɔwɔ kple atikewo wɔwɔ me. Ewɔa nu aduadu kplikplikpli kple dɔwɔƒe kple dɔwɔƒe xɔŋkɔ geɖewo, siwo dometɔ aɖewoe nye Organizations Concentr Analges Inc, Teichman Drug Dev Consulting, Wroclaw Medical University, BEAT Biotherapeut Corp, Corthera Inc kple eƒe dɔwɔƒe si do ƒome kplii Corthera, Chiasma, ARYx Therapeut Inc, kple bubuawo Tsɔ kpe ɖe eŋu la, edo ƒome kple sukuwo hã abe University of Athens Hospital kple Albert Einstein College of Atikewɔwɔ, si ɖee fia be enya nu geɖe tso atikewɔwɔ ŋuti numekuku kple atikewɔnyawo me. Eƒe dɔwɔwɔ ƒe akpa vovovowo ku ɖe akpa vovovowo abe dzitodzito kple dzidɔ, ememe atikewɔwɔ kple dɔwɔwɔ le mɔ gbadza nu, mɔ̃ɖaŋudɔwɔwɔ, lãmenugbagbeviwo ƒe dɔwɔwɔ kple lãmenugbagbeviwo ƒe dɔwɔwɔ, kple atikeŋutinunya kple atikeŋutinunya, vevietɔ kple dzidzedzekpɔkpɔ ɖedzesiwo kple akpa si wòwɔ le atikewo wɔwɔ kple nugbagbewo ƒe atikewɔwɔ me. Woŋlɔ Teichman SL ŋkɔ ɖe nyayɔyɔ ƒe nyatakaka me [1].
