|
1kits (10Vials) .
| Agbɔsɔsɔ: | |
|---|---|
▎ Sema ƒe Dɔwɔɖoɖo
Dzɔtsoƒe: PubChem |
Nusiwo kplɔ wo nɔewo ɖo: MEHFPGP Molekyulãwo ƒe Mɔfiame: C 37H 51N 9O 10S Molekyulãwo ƒe Kpekpeme: g/mol CAS ƒe xexlẽdzesi: 80714-61-0 PubChem ƒe CID: 9811102 Nya siwo sɔ kple wo nɔewo: ACTH (4-7) |
▎ Sema Numekuku
Nukae nye Sema?
Sema nye peptide ƒe atike si wowɔ eye wòle nootropic ƒomevi aɖe me. Eƒe akpa vevitɔe nye thyrotropin-releasing hormone (TRH) ƒe kpeɖeŋutɔ, si wotsɔ tsaka kple amino acid bubuwo (abe valine kple leucine ene). Sema ate ŋu ana susu ƒe dɔwɔwɔ nanyo ɖe edzi to ahɔhɔ̃mekawo (abe dopamine kple norepinephrine ene) dzi kpɔkpɔ le lãmekawo ƒe dɔwɔwɔ me, si ƒe ɖewoe nye ŋkuɖoɖonudzi dzi ɖeɖe kpɔtɔ, susu ƒe dɔwɔwɔ nyuie wu, kple nusɔsrɔ̃ ƒe ŋutete dodo ɖe ŋgɔ.
Nukae nye Sema ƒe numekuku?
Dɔwɔwɔ si wotu ɖe ACTH kakɛwo dzi:
Sema nye ACTH (4 - 7) kakɛ kple tripeptide Pro - Gly - Pro (PGP) ƒe ƒuƒoƒo. ACTH, si nye adrenocorticotropic hormone, nye lãmetsi si le ŋgɔgbe lãkusi me eye wòwɔa akpa vevi aɖe le adrenal cortex ƒe dɔwɔwɔ dzi kpɔkpɔ me. Numekulawo ku ACTH ƒe wɔwɔme me, woɖe kakɛ aɖe koŋ (4 - 7) tso eme, eye wotsɔe ƒo ƒu kple tripeptide PGP tsɔ wɔ Sema. Nuwɔwɔ ƒe mɔnu sia nana Sema te ŋu léa ACTH ƒe dɔwɔwɔ ƒe akpa aɖe me ɖe asi eye nugbagbe ƒe nɔnɔme tɔxɛwo hã le esi [1] ..
Asrãdɔ dada ƒe numekuku:
Aɖuɖɔtoe nye ahɔhɔ̃ ƒe dɔwɔwɔ ƒe kuxi si ƒe dzesi enye ahɔhɔ̃mekawo ƒe ʋuʋu le mɔ si mesɔ o nu. Aɖuɖɔtoe nye asrãdɔ ƒe dzesi vevi aɖe, eye zi geɖe la, ahɔhɔ̃ ƒe abixɔxɔ gbɔe wòtsona. Togbɔ be atike siwo wozãna fifia tsɔ daa asrãdɔ kpɔa ŋusẽ aɖewo hã la, wokpɔa ŋusẽ gbegblẽ aɖewo hã ɖe lãmesẽ dzi. Le nɔnɔme sia me la, numekulawo te atikewɔwɔmɔnu yeyewo didi. Abe neuropeptide ene la, Sema peptide wɔa dɔ ɖe lãmekawo ƒe dɔwɔwɔ dzi tẽ eye lãmetsiŋusẽ ƒe dɔwɔwɔ aɖeke mele eŋu o, eyata mahe ŋusẽ gbegblẽ ɖe lãmesẽ dzi o. Esia na mɔnukpɔkpɔ yeyewo li be woatsɔ ada asrãdɔ [2] ..
Atikewɔwɔ na ʋusɔgbɔdɔ si me ʋu sina tona:
Ischemic stroke nye dɔléle sesẽ aɖe, eye le eƒe dzɔdzɔ geɖe kple nuwɔametɔwo ƒe agbɔsɔsɔ gã ta la, enye nusi ŋu wotsia dzi ɖo le atikewɔwɔ me numekukuwo me ɣesiaɣi. Wozãa sema peptide, le eƒe ahɔhɔ̃mekawo takpɔkpɔ kple dɔlélenutsiŋutete ƒe dɔwɔwɔ ta, tsɔ daa ʋusɔgbɔdɔ si me ʋu sina tona. Numekukuwo ɖee fia be Sema ateŋu axe mɔ na dɔdzẽ ƒe domenyiŋusẽfianuwo ƒe ɖeɖefia eye wòana ahɔhɔ̃mekawo ƒe dɔwɔwɔ ƒe domenyiŋusẽfianuwo ƒe ɖeɖefia nawɔ dɔ, si wɔnɛ be wòawɔ ahɔhɔ̃mekawo takpɔkpɔ ƒe ŋusẽkpɔɖeamedziwo le nuŋɔŋlɔ kple protein ƒe agbɔsɔsɔ me [3, 4]..
Mɔfiame yeye aɖe si woatsɔ ada blanuiléle:
Selective serotonin reuptake inhibitors (SSRI) nye atike siwo wozãna zi geɖe tsɔ daa blanuiléle le fufɔɣi, gake SSRI ate ŋu atso vidzidɔa eye ate ŋu akpɔ ŋusẽ ɖe fugboe ƒe ahɔhɔ̃ ƒe tsitsi dzi. Abe ACTH (4-10) ƒe nɔnɔmetata si wowɔ ene la, nootropic kple ahɔhɔ̃mekawo takpɔkpɔ ƒe dɔwɔna siwo dze ƒã le Sema si. Numekukuwo ɖee fia be Sema ate ŋu aɖe tɔtrɔ siwo vaa sisiblisiwo ƒe nuwɔna kple ahɔhɔ̃mekawo ƒe dɔwɔwɔ me le fluvoxamine zazã kaba ta dzi akpɔtɔ, si naa susu yeye aɖe le blanuiléle dada ŋu [5]..
Viɖe siwo le peptide-nu siwo wozãna ŋu:
Sema nye peptide-nu si wowɔ eye eƒe dɔwɔwɔ ƒe mɔnu tɔxɛ aɖe le esi. Ate ŋu awɔ dɔ ɖe lãmekawo ƒe dɔwɔwɔ dzi tẽ, awɔ protein aɖewo le ahɔhɔ̃a me, eye wòawɔ dɔ ɖe dɔlélenutsiŋutete dzi. Le kpɔɖeŋu me, le asrãdɔ ƒe kpɔɖeŋu si wowɔ le sisiblisi me la, Sema peptide ate ŋu aɖe MDA ƒe agbɔsɔsɔ dzi akpɔtɔ eye wòawɔ protein etɔ̃ siwo womewɔ le sisiblisi siwo ŋu asrãdɔ le me o [2]..
Abe ɖoɖowɔɖi ƒe peptide ene la, woate ŋu akpɔ Sema ƒe numekuku ŋutinya tso ɣeyiɣi didi aɖee nye sia. Numekukuwo ɖee fia be mɔkpɔkpɔ li be woazã Sema le ŋkuɖoɖonudzi ƒe kuxiwo, susu ƒe dɔwɔwɔ nyuie ƒe ɖiɖi, kple COVID megbe dɔléle me, tsɔ kpe ɖe somatoform kple susumedɔlélewo ŋu [6] ..
Tɔtrɔ siwo va le pJNK kple pCREB proteinwo ƒe agbɔsɔsɔ me me dzodzro le ischemia kple Sema dɔdamɔnu me le subcortical structures kple frontoparietal cortex me le sisiblisiwo me le 24 h le tMCAO megbe.
Dzɔtsoƒe:PubMed [4] .
Aleke Sema ƒe dɔwɔwɔ le asrãdɔ dada me kpɔa ŋusẽ ɖe ahɔhɔ̃a ƒe dɔwɔwɔ dzi koŋ?
Antioxidant ƒe ŋusẽkpɔɖeamedzi
Nusiwo tsia dzoxɔxɔ nu le sema ŋu. Zi geɖe la, asrã nana oxidative stress dzina ɖe edzi le ahɔhɔ̃a me, eye Sema ate ŋu aɖe nusiwo oxidative stress gblẽna le ahɔhɔ̃a ŋu dzi akpɔtɔ. Oxidative stress ana oxygen ƒomevi siwo wɔa dɔ fũ akpa, abe malondialdehyde (MDA) ene, nado. Numekukuwo ɖee fia be Sema ateŋu aɖe MDA ƒe agbɔsɔsɔ dzi akpɔtɔ le ahɔhɔ̃ me le sisiblisi siwo ŋu asrãdɔ le me va ɖo 40.46% [2] . To MDA ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ me la, Sema ate ŋu aɖe oxidative stress ƒe nugbegblẽ le ahɔhɔ̃mekawo ŋu dzi akpɔtɔ, si ana ahɔhɔ̃a ƒe dɔwɔwɔ ta.
Ahɔhɔ̃ me proteinwo ƒe wɔwɔme
Sema te ŋu wɔa protein aɖewo le ahɔhɔ̃a me. Le numekuku si wowɔ le sisiblisi siwo ŋu asrãdɔ le ŋu me la, le atikewɔwɔ kple Sema megbe la, wowɔ protein etɔ̃ siwo womewɔ le sisiblisi siwo ŋu asrãdɔ le me o. Protein siawo ƒe molecule ƒe kpekpeme nye 93.54kDa, 66.76kDa, kple 59.66kDa [2] . Woate ŋu awɔ akpa vevi aɖe le ahɔhɔ̃a ƒe dɔwɔwɔ nyuie me léle ɖe asi kple ahɔhɔ̃meka siwo gblẽ la dzadzraɖo me.
Ŋusẽkpɔɖeamedzi ɖe ahɔhɔ̃mekawo ƒe dɔwɔwɔ dzi
To gbɔɖeme-nɔnɔme ƒe dɔwɔwɔ magnetic resonance imaging (gbɔɖeme-nɔnɔme FMRI) numekukuwo me la, wokpɔe be Sema kpɔa ŋusẽ ɖe ahɔhɔ̃mekawo ƒe kadodo dzi. Le lɔlɔ̃nu faa dɔwɔla siwo le lãmesẽ me ŋuti numekuku me, ne wotsɔe sɔ kple ƒuƒoƒo si me wokpɔa wo gbɔ le la, wokpɔ rostral (intermediate anterior cortex) sub-component of the default mode network ƒe lolome si lolo wu le Sema ƒuƒoƒoa me [7] . Esia ɖee fia be Sema ate ŋu ana ahɔhɔ̃a ƒe dɔwɔwɔ nanyo ɖe edzi to ahɔhɔ̃mekawo ƒe kadodo kple dɔwɔwɔwo dzi kpɔkpɔ me.
Esi wodo Sema gbesiagbe ɖe sisiblisi siwo ƒe aɖuɖɔtoe ƒe alɔ̃madɔmadɔ bɔbɔe me tso woƒe agbenɔƒe ƒe ŋkeke 7 lia va ɖo 11 lia dzi la, wokpɔe be gbetedziawo ƒe alɔ̃madɔmadɔ ƒe ɖoɖo si me wosena le la trɔna ne woxɔ ɣleti 1, eye atike eveawo siaa ate ŋu ana ahɔhɔ̃mekawo ƒe dɔwɔwɔ nadzi ɖe edzi le hippocampal dentate gyrus me. Ahɔhɔ̃mekawo ƒe dzɔdzɔ ate ŋu ado ƒome kple ahɔhɔ̃a ƒe nusɔsrɔ̃, ŋkuɖoɖonudzi, kple nuwo ɖɔɖɔɖodɔwo, eye Sema ate ŋu ana ahɔhɔ̃a ƒe dɔwɔwɔ nanyo ɖe edzi to ahɔhɔ̃mekawo ƒe dɔwɔwɔ dodo ɖe ŋgɔ me.
Esi wodo Sema ɖe vidzĩ yeyewo ƒe sisiblisi ƒomevi atɔ̃ siwo wodzi le wo ɖokui me (tso woƒe agbemeŋkeke 2 lia dzi va ɖo ŋkeke 7 lia dzi) la, eɖe alesi woate ŋu aʋuʋui bɔbɔe le DBA / 2J mice siwo xɔ ɣleti 1 ko me [8] . Esia ɖee fia hã be Sema ate ŋu akpɔ ŋusẽ ɖe ahɔhɔ̃a ƒe dɔwɔwɔ dzi to mɔnu aɖe dzi eye wòaɖe alesi wòate ŋu axɔ asrãdɔ dzi akpɔtɔ.
Lãmetsiŋusẽ ƒe dɔwɔwɔ ƒe anyimanɔmanɔ
Sema nye neuropeptide si wɔa dɔ ɖe titina lãmekawo dzi tẽ eye lãmetsiŋusẽ ƒe dɔwɔwɔ aɖeke mele eŋu o, eyata mahe lãmesẽkuxi gbegblẽwo vɛ o (Puspita R, 2018). Esia naa viɖe aɖewo Sema le asrãdɔ dada me, si wɔnɛ be wòƒoa asa na atike siwo wozãna tsã siwo wua asrãdɔ ƒe nugbegblẽ le ame ŋu.
Nukae nye mɔnu tɔxɛ si dzi Sema tona ɖɔa dɔlélenutsiŋutete ƒe dɔwɔwɔ ɖo?
Dzesimɔ siwo do ƒome kple dɔlélenutsiŋutete ƒe dɔwɔwɔ nyuie dodo ɖe ŋgɔ:
Sema ate ŋu ana antigen ƒe ɖeɖefia ƒe dzesimɔa nanyo ɖe edzi. Antigen ƒe ɖeɖefia nye nu vevi aɖe si dɔlélenutsiŋutete te ŋu dea dzesi duta antigenwo hewɔa dɔ tso wo ŋu. To dzesimɔ sia dodo ɖe ŋgɔ me la, Sema ate ŋu ado dɔlélenutsiŋutete ƒe dzesidede kple alesi wòwɔa nu ɖe dutanuwo abe dɔlékuiwo ene ŋu ɖe ŋgɔ [1] . Tsɔ kpe ɖe eŋu la, Sema ate ŋu ado ŋusẽ ŋusẽ si ʋumenugbagbeviɣidɔ kpɔna ɖe interferon ƒe dzesimɔ dzi hã. Interferon wɔa akpa vevi aɖe le ɖoɖowɔwɔ me le dɔlélenutsiŋutete ƒe dɔwɔwɔ me, siwo dometɔ aɖewoe nye dɔlékuiwutike, dɔlékuiwutike, kple dɔlélenutsiŋutete ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi kpɔkpɔ. Sema ƒe ŋusẽdodo interferon ƒe dzesimɔa kpena ɖe ame ŋu be dɔlélenutsiŋutete ƒe dɔwɔwɔ bliboa nanyo ɖe edzi [1]..
Ŋusẽkpɔɖeamedzi ɖe dɔlélenutsiŋutete ƒe wɔwɔme ƒe ɖoɖoa dzi:
Sema dzia domenyiŋusẽfianu siwo ŋlɔa dɔlélenutsiŋutete ƒe kɔsɔkɔsɔ kpekpewo ƒe ɖeɖefia ɖe edzi ŋutɔ. Dɔlékuiwutikewo wɔa akpa vevi aɖe le humoral dɔlélenutsiŋutete me eye woate ŋu abla ɖe dɔlékuiwutikewo ŋu koŋ, si wɔnɛ be dutanuwo abe dɔlékuiwo ene ɖa. Sema doa dɔlélenutsiŋutete ƒe wɔwɔme ɖe ŋgɔ, si kpena ɖe ŋutilã ƒe dɔlélenutsiŋutete ƒe dɔwɔwɔ le humoral me ŋu [1] ..
Dɔlélenutsiŋutete ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ dzi kpɔkpɔ:
Sema kpɔa ŋusẽ gã aɖe ɖe domenyiŋusẽfianu siwo ŋlɔa cytokines, nuteɖeamedzi ƒe ŋuɖoɖo, kple ribosomal proteinwo dzi. Cytokines wɔa akpa vevi aɖe le dɔlélenutsiŋutete ƒe tɔtrɔ me eye woate ŋu aɖɔ dɔlélenutsiŋutete ƒe lãmenugbagbeviwo ƒe dzidziɖedzi, vovototodedeameme, kple dɔwɔwɔ ɖo. Sema ɖɔa dɔlélenutsiŋutete ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ɖo to ŋusẽkpɔkpɔ ɖe domenyiŋusẽfianu siawo ƒe ɖeɖefia dzi, si wɔnɛ be wòɖɔa dɔlélenutsiŋutete ƒe dɔwɔwɔ ɖo [1] ..
Nukae nye Seamx ƒe dɔwɔwɔwo?
Atikewɔwɔ na asrãdɔ
Ŋusẽkpɔɖeamedzi ɖe ahɔhɔ̃mekawo dzi:
Aɖuɖɔtoe nye ahɔhɔ̃ ƒe dɔwɔwɔ ƒe kuxi si ƒe dzesi enye ahɔhɔ̃mekawo ƒe ʋuʋu le mɔ si mesɔ o nu. Sema peptide nye ahɔhɔ̃meka si wɔa dɔ ɖe lãmekawo ƒe dɔwɔwɔ dzi tẽ eye lãmetsiŋusẽ ƒe dɔwɔwɔ mele eme o, eyata makpɔ ŋusẽ gbegblẽ ɖe lãmesẽ dzi o. Sema ate ŋu aɖe MDA ƒe agbɔsɔsɔ dzi akpɔtɔ le sisiblisi siwo ŋu asrãdɔ le ƒe ahɔhɔ̃ me. MDA nye nusi fia be lipid peroxidation, eye MDA ƒe agbɔsɔsɔ si sɔ gbɔ do ƒome kple oxidative stress kple lãmenugbagbeviwo ƒe gbegblẽ. Sema ateŋu aɖe MDA ƒe agbɔsɔsɔ dzi akpɔtɔ le ahɔhɔ̃ me le sisiblisi siwo ŋu asrãdɔ le me va ɖo 40.46% [9]..
Proteinwo ƒe wɔwɔme:
Sema ate ŋu awɔ protein aɖewo le sisiblisi siwo ŋu asrãdɔ le ƒe ahɔhɔ̃ me hã. Numekukuwo ɖee fia be Sema ateŋu awɔ protein etɔ̃ siwo womewɔ le gɔmedzedzea me le sisiblisi siwo ŋu asrãdɔ le ƒe ahɔhɔ̃ me o, eye protein siawo ƒe molecule ƒe kpekpeme nye 93.54 kDa, 66.76 kDa, kple 59.66 kDa [9]..
Atikewɔwɔ na ʋusɔgbɔdɔ si me ʋu sina tona
Neurotrophin ƒe nuŋɔŋlɔ dodo ɖe ŋgɔ:
Sema (MET-GLU - amino acid - phenylalanine - proline - glycine - proline) peptide nye melanocortin ƒe atike si wowɔ si wozãna tsɔ daa ʋusɔgbɔdɔ si me ʋu sina tona. Numekukuwo ɖee fia be Sema ate ŋu ana neurotrophins kple woƒe xɔlawo ƒe nuŋɔŋlɔ nanyo ɖe edzi eye wòatrɔ asi le domenyiŋusẽfianu siwo kpɔa gome le dɔlélenutsiŋutete ƒe dɔwɔwɔ me ƒe ɖeɖefia ŋu. Whole-genome RNA sequencing analysis ɖee fia be le transient middle cerebral artery occlusion (tMCAO) model le sisiblisiwo me la, Sema xea mɔ na dɔdzẽ ƒe domenyiŋusẽfianuwo ƒe ɖeɖefia eye wònaa ahɔhɔ̃mekawo ƒe dɔwɔwɔ ƒe domenyiŋusẽfianuwo ƒe ɖeɖefia wɔa dɔ [4]..
Protein veviwo ƒe ɖeɖefia dzi kpɔkpɔ:
Le gaƒoƒo 24 le tMCAO megbe la, wokpɔ CREB si le dɔ wɔm ƒe dziyiyi le subcortical structures me, si me ischemic injury ƒe susu nɔ; Woɖe MMP - 9 kple c - fos dzi kpɔtɔ le frontoparietal cortex si te ɖe eŋu me; le Sema ƒe dɔwɔwɔ te la, woɖe JNK si le dɔ wɔm hã dzi kpɔtɔ le lãkusi eve siawo me. Mɔxexe ɖe dɔwɔwɔ nu kple eƒe hayahaya le dɔdzẽ kple lãmenugbagbeviwo ƒe ku ƒe dɔwɔwɔwo me ate ŋu awɔ akpa aɖe le Sema ƒe ahɔhɔ̃mekawo takpɔkpɔ ƒe ŋusẽkpɔɖeamedzi le nuŋɔŋlɔ kple protein ƒe agbɔsɔsɔ me [4] ..
Nuteɖeamedzi sesẽwo dzi ɖeɖe kpɔtɔ
Vevesese dzi ɖeɖe kpɔtɔ:
Le nuteɖeamedzi sesẽ ƒe kpɔɖeŋu me la, Sema kpɔa ŋusẽ aɖe ɖe sisiblisiwo ƒe nuwɔna kple vevesese ƒe seselelãme dzi. Le afɔ ƒe ʋuʋu ƒe nuteɖeamedzi si womate ŋu asi le o kple tsi fafɛ tsiƒuƒu ƒe nuteɖeamedzi ƒe kpɔɖeŋuwo me la, Sema kple opioid xɔla ƒe mɔxenu naloxone siaa ateŋu aɖe vevesesenutsitike si nuteɖeamedzi hena vɛ (SIA) dzi akpɔtɔ le afɔ ƒe ʋuʋu ƒe nuteɖeamedzi si womate ŋu asi le o ƒe kpɔɖeŋu me, gake womekpɔa ŋusẽ ɖe vevesese ƒe dzidzenu dzi le tsi fafɛ tsiƒuƒu ƒe nuteɖeamedzi ƒe kpɔɖeŋu me o [10]..
Ŋusẽkpɔɖeamedzi aɖeke mele nuwɔna ƒe tɔtrɔwo ŋu o:
Sema kple naloxone siaa mekpɔa ŋusẽ ɖe sisiblisiwo ƒe nuwɔna dzi le nuteɖeamedzi sesẽ ƒe kpɔɖeŋu siwo le etame me o [10]..
Ŋkuɖoɖonudzi kple susu ƒe dɔwɔwɔ nyuie wu:
Sema ate ŋu aʋã lãwo kple amegbetɔ siwo le dodokpɔ me ƒe ŋkuɖoɖonudzi kple susu si le dɔ wɔm, ana tsitretsitsi ɖe ya si mebɔ o ŋu nadzi ɖe edzi, eye wòana ahɔhɔ̃ me ʋu nazɔ nyuie wu. Sema nana ame siwo le lãmesẽ me ƒe ŋkuɖoɖonudzi kple susu nyona ɖe edzi ŋutɔ le dɔwɔna siwo gbɔ eme ƒe nɔnɔmewo me. Tsɔ kpe ɖe eŋu la, wozã Sema dzidzedzetɔe fifia tsɔ da dɔnɔ siwo ŋu lãmekawo ƒe dɔléle vovovowo le. Zi geɖe la, peptide sia ɖea ŋusẽkpɔɖeamedzi nyuiwo fiana evɔ mehea nugbegblẽ le ame ŋu alo kuxi siwo do ƒome kple edodo vɛ o [11]..
Le nyataƒoƒo me la, abe peptide ƒe atike si wowɔ ene la, Sema ɖea dɔyɔyɔ ƒe ŋusẽkpɔɖeamedzi veviwo fiana le asrãdɔ, ʋusɔgbɔdɔ, nuteɖeamedzi sesẽ, kple susu ƒe dɔmawɔmawɔ nyuie ƒe akpawo me to mɔnu vovovowo abe neurotrophins (abe BDNF) kple woƒe xɔlawo (TrkB) ƒe ɖeɖefia dzi kpɔkpɔ dzi kpɔkpɔ, mɔxexe ɖe dɔdzẽ ƒe ŋuɖoɖo nu, tsitretsitsi ɖe oxidative stress ŋu, kple dɔlélenutsiŋutete ƒe tɔtrɔ. Ate ŋu ana lãmekawo ƒe dɔwɔwɔ nanyo ɖe edzi hã, aɖe ahɔhɔ̃a ƒe gbegblẽ dzi akpɔtɔ, eye wòana ŋkuɖoɖonudzi kple susu nanɔ nu ŋu nanyo ɖe edzi.
Le Agbalẽŋlɔla La Ŋu
Nusiwo míeyɔ ɖe etame la katã nye esiwo ŋu Cocer Peptides wɔ numekuku le, trɔ asi le wo ŋu eye woƒo wo nu ƒu.
Dzɔdzɔmeŋutinunya ƒe Agbalẽŋlɔla
Sudarkina OY nye numekula si do ƒome kple Dukɔa ƒe Numekuku Dɔwɔƒe - Kurchatov Dɔwɔƒe kple Russia Dzɔdzɔmeŋutinunya Suku. Eƒe numekuku siwo me wòtsɔ ɖe le la ku ɖe dzɔdzɔmeŋutinunya me nu vovovowo ŋu, siwo dometɔ aɖewoe nye Biochemistry & Molecular Biology, Genetics & Heredity, kple Chemistry. Ewɔ akpa vevi aɖe le Nu Gbagbewo Ŋuti Mɔ̃ɖaŋununya, Molecular Breeding, kple Molecular Plant Pathology ƒe akpawo me. Eƒe dɔa lɔ domenyiŋusẽfianu ƒe dɔwɔwɔ, molecule ƒe kadodo, kple nugbagbeŋusẽ ƒe dɔwɔwɔ siwo doa alɔ nugbagbewo ƒe nudzɔdzɔ vovovowo sɔsrɔ̃ ɖe eme. To eƒe numekukua dzi la, eɖoe be yeado míaƒe gɔmesese ɖe ŋgɔ le ɖoɖo sesẽ siawo ŋu eye yeato egbɔkpɔnu yeyewo vɛ hena wo zazã ŋutɔŋutɔ le agbledede, atikewɔwɔ, kple dɔwɔƒe bubuwo me. Woŋlɔ Sudarkina OY ŋkɔ ɖe nyayɔyɔ ƒe nyatakaka me [4].
